L-Phenylalanine-d is a deuterium-labeled form of the essential amino acid L-Phenylalanine, which serves as a stable isotope. This compound acts as an antagonist to the α2δ subunit of voltage-dependent calcium channels, exhibiting a Ki value of 980 nM. Additionally, L-Phenylalanine-d competitively inhibits glycine- and glutamate-binding sites on N-methyl-D-aspartate receptors (NMDARs) with a KB of 573 μM. It finds applications in research related to neuropharmacology and the synthesis of various pharmaceuticals and food flavorings.
L-Phenylalanine-d is a deuterium-labeled form of the essential amino acid L-Phenylalanine, which serves as a stable isotope. This compound acts as an antagonist to the α2δ subunit of voltage-dependent calcium channels, exhibiting a Ki value of 980 nM. Additionally, L-Phenylalanine-d competitively inhibits glycine- and glutamate-binding sites on N-methyl-D-aspartate receptors (NMDARs) with a KB of 573 μM. It finds applications in research related to neuropharmacology and the synthesis of various pharmaceuticals and food flavorings.
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