LASSBio-2389 is a selective inhibitor of Rho-associated protein kinase 2 (ROCK2) with an IC50 of 0.051 μM and demonstrates lower potency against ROCK1 with an IC50 of 1.143 μM. This compound effectively reduces the viability of MDA-MB-231 cells and inhibits cell migration, making it a valuable tool for investigating the pathophysiology of triple-negative breast cancer. Its targeted action on ROCK2 positions LASSBio-2389 as a significant reagent in cancer research applications focused on aggressive tumor behaviors.
LASSBio-2389 is a selective inhibitor of Rho-associated protein kinase 2 (ROCK2) with an IC50 of 0.051 μM and demonstrates lower potency against ROCK1 with an IC50 of 1.143 μM. This compound effectively reduces the viability of MDA-MB-231 cells and inhibits cell migration, making it a valuable tool for investigating the pathophysiology of triple-negative breast cancer. Its targeted action on ROCK2 positions LASSBio-2389 as a significant reagent in cancer research applications focused on aggressive tumor behaviors.
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