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LCC-12 formic

Catalog No.: A48067
Bacterial Inhibitor
LCC-12 formic is a dimer of metformin that acts as a bacterial inhibitor through its interaction with mitochondrial copper(II), resulting in a reduction of the NAD(H) pool and modulation of inflammatory responses. This compound has demonstrated the ability to decrease inflammation in mouse models of bacterial and viral infections. Additionally, LCC-12 formic is utilized as a research tool to explore metabolic diseases, focusing on its impact on cell plasticity and epigenetic programming.
LCC-12 formic 3029253-76-4 Bacterial Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$125.00
In stock
5mg
$325.00
In stock
10mg
$495.00
In stock
25mg
$780.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLCC-12 formic is a dimer of metformin that acts as a bacterial inhibitor through its interaction with mitochondrial copper(II), resulting in a reduction of the NAD(H) pool and modulation of inflammatory responses. This compound has demonstrated the ability to decrease inflammation in mouse models of bacterial and viral infections. Additionally, LCC-12 formic is utilized as a research tool to explore metabolic diseases, focusing on its impact on cell plasticity and epigenetic programming.
Product Information
Catalog NumA48067
FormulaC18H40N10O4
Molecular Weight460.57
CAS Number3029253-76-4
SMILESO=CO.N=C(NC(NCCCCCCCCCCCCNC(NC(N)=N)=N)=N)N.O=CO
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Microbiology > Antifection > Bacterial