LEI-101 free base is a selective and orally bioavailable agonist of the CB2 receptor, primarily targeting inflammation and oxidative stress-related conditions. It demonstrates a binding potency to CB2 receptors that is approximately 100 times greater than its affinity for CB1 receptors, with a pEC50 value of 8. The compound’s pharmacological profile suggests potential applications in the treatment of diseases such as kidney disease, making it valuable in therapeutic research.
LEI-101 free base is a selective and orally bioavailable agonist of the CB2 receptor, primarily targeting inflammation and oxidative stress-related conditions. It demonstrates a binding potency to CB2 receptors that is approximately 100 times greater than its affinity for CB1 receptors, with a pEC50 value of 8. The compound’s pharmacological profile suggests potential applications in the treatment of diseases such as kidney disease, making it valuable in therapeutic research.
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