Lenalidomide-d4 is a deuterium-labeled derivative of Lenalidomide, functioning as a stable isotope for advanced chemical research. As an orally active immunomodulator, Lenalidomide targets the cereblon (CRBN) ubiquitin E3 ligase, leading to the selective ubiquitination and degradation of transcription factors IKZF1 and IKZF3. This activity is particularly relevant in the context of mature B-cell lymphomas, including multiple myeloma, where Lenalidomide-d4 has been shown to inhibit tumor growth and promote IL-2 release from T cells. This reagent is suitable for studies in drug mechanisms and development within the field of oncology.
Lenalidomide-d4 is a deuterium-labeled derivative of Lenalidomide, functioning as a stable isotope for advanced chemical research. As an orally active immunomodulator, Lenalidomide targets the cereblon (CRBN) ubiquitin E3 ligase, leading to the selective ubiquitination and degradation of transcription factors IKZF1 and IKZF3. This activity is particularly relevant in the context of mature B-cell lymphomas, including multiple myeloma, where Lenalidomide-d4 has been shown to inhibit tumor growth and promote IL-2 release from T cells. This reagent is suitable for studies in drug mechanisms and development within the field of oncology.
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