Lifirafenib

Catalog No.: A20988

Raf/EGFR inhibitor

Lifirafenib

Lifirafenib Chemical Structure

CAS NO. 1446090-77-2

Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$242.00
50 mg
$718.00
100 mg
$1,435.00
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Biological Activity

Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.9 mL 104.51 mL 209.02 mL
0.5 mM 4.18 mL 20.9 mL 41.8 mL
1 mM 2.09 mL 10.45 mL 20.9 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20988
Actions Inhibitor
M. Wt 478.42
Formula C25H17F3N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1446090-77-2
Synonyms BGB-283, BGB283, BGB 283
SMILES FC(F)(F)C(C=C1)=CC2=C1N=C(N2)[[email protected]@H]3[[email protected]]([[email protected]@H]43)OC(C4=C5)=CC=C5OC6=CC=NC(N7)=C6CCC7=O

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