LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development.
LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development.
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