LND 796 is a calcium channel agonist with positive inotropic effects reminiscent of digitalis. It demonstrates a concentration-dependent increase in contractility in guinea pig papillary muscles, enhancing both contraction components and slow action potential amplitude, particularly in partially potassium-depolarized conditions. The mechanism of action involves increased calcium influx through calcium channels and inhibition of sodium-potassium ATPase. Due to its unique profile, LND 796 may have potential applications in the treatment of congestive heart failure.
LND 796 is a calcium channel agonist with positive inotropic effects reminiscent of digitalis. It demonstrates a concentration-dependent increase in contractility in guinea pig papillary muscles, enhancing both contraction components and slow action potential amplitude, particularly in partially potassium-depolarized conditions. The mechanism of action involves increased calcium influx through calcium channels and inhibition of sodium-potassium ATPase. Due to its unique profile, LND 796 may have potential applications in the treatment of congestive heart failure.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
