Lomefloxacin hydrochloride is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. It exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and induces reactive oxygen species (ROS) production, leading to apoptosis. Additionally, Lomefloxacin hydrochloride demonstrates anticancer effects, particularly against melanoma, making it a valuable reagent for studying systemic bacterial infections and skin malignancies.
Lomefloxacin hydrochloride is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. It exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and induces reactive oxygen species (ROS) production, leading to apoptosis. Additionally, Lomefloxacin hydrochloride demonstrates anticancer effects, particularly against melanoma, making it a valuable reagent for studying systemic bacterial infections and skin malignancies.
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