Luzopeptin A

Catalog No.: A46826
Antitumor Antibiotic
Luzopeptin A is an actinoleukin-like antitumor antibiotic that functions primarily as a bifunctional DNA intercalator. It engages with isolated DNA molecules, inducing unwinding and rewinding processes in superhelical PM2 DNA. Additionally, Luzopeptin A exhibits potent activity against HIV-1 and HIV-2 reverse transcriptases, with IC50 values of 7 nM and 68 nM, respectively. This compound is valuable for research applications in cancer therapy and virology.
Grouped product items
Size Price Stock Qty
1mg
$590.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Cell Vol. 185 Issue 23 p4428-4447.e28
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionLuzopeptin A is an actinoleukin-like antitumor antibiotic that functions primarily as a bifunctional DNA intercalator. It engages with isolated DNA molecules, inducing unwinding and rewinding processes in superhelical PM2 DNA. Additionally, Luzopeptin A exhibits potent activity against HIV-1 and HIV-2 reverse transcriptases, with IC50 values of 7 nM and 68 nM, respectively. This compound is valuable for research applications in cancer therapy and virology.
Product Information
Catalog NumA46826
FormulaC64H78N14O24
Molecular Weight1427.38
CAS Number75580-37-9
SMILESO=C1N2[C@@](C(NCC(N(CC(N([C@H](C(OC[C@H](C(N3[C@]([C@H](CC=N3)OC(C)=O)([H])C(NCC(N(CC(N([C@H](C(OC[C@H]1NC(C4=NC5=C(C=C(C=C5)OC)C=C4O)=O)=O)C(C)(O)C)C)=O)C)=O)=O)=O)NC(C6=NC7=C(C=C(C=C7)OC)C=C6O)=O)=O)C(C)(O)C)C)=O)C)=O)=O)([H])[C@H](CC=N2)OC(C)=O
SynonymsBBM-928 A
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