Fig. 1 · Structure
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Lysophosphatidylethanolamines, egg
Cat. No.
A71429
CAS
97281-40-8
Endogenous Metabolite
Lysophosphatidylethanolamines (LPE) are endogenous lysophospholipids generated through the deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). LPE is known to enhance ERK1/2 phosphorylation in PC12 cells, an effect that can be attenuated by MEK inhibitors such as U-0126 and PD 98059, as well as the EGFR inhibitor AG-1478. Additionally, LPE promotes neurite outgrowth and increases neurofilament M expression in these cells. This product encompasses various molecular species of lysophosphatidylethanolamine characterized by differing fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position, making it suitable for diverse biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 97281-40-8 |
| Applications | Endogenous Metabolite |
| Formula | N/A |
| Synonyms | Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.