m-PEG2-azide is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool for the development of targeted protein degradation strategies. Its applications are essential for advancing research in protein modulation and therapeutic development.
m-PEG2-azide is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool for the development of targeted protein degradation strategies. Its applications are essential for advancing research in protein modulation and therapeutic development.
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