Menoxymycin B

Catalog No.: A47722
Antitumor Antibiotic
Menoxymycin B is an antitumor antibiotic that exhibits notable cytotoxic effects against cancer cells. It demonstrates potent inhibitory activity with IC50 values of 0.22 μM in KB cells and 0.023 μM in N18-RE-105 cells. This compound is valuable for cancer research, particularly in studies focused on cell proliferation and apoptosis mechanisms.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMenoxymycin B is an antitumor antibiotic that exhibits notable cytotoxic effects against cancer cells. It demonstrates potent inhibitory activity with IC50 values of 0.22 μM in KB cells and 0.023 μM in N18-RE-105 cells. This compound is valuable for cancer research, particularly in studies focused on cell proliferation and apoptosis mechanisms.
Product Information
Catalog NumA47722
FormulaC25H31NO9
Molecular Weight489.51
CAS Number160523-76-2
SMILESO=C1C2=C([C@H](O[C@@H]([C@@H]2O)CC(OC)=O)C)C(C3=C(O)C([C@H]4C[C@H]([C@@H]([C@H](O4)C)O)N(C)C)=CC=C31)=O
Useful Calculator

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