Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
EcMetAP1-IN-1 is a selective inhibitor of Escherichia coli methionine aminopeptidase 1 (MetAP1), a key enzyme involved in protein maturation. By obstructing the enzymatic activity of MetAP1, this compound effectively disrupts bacterial growth and protein synthesis, making it a valuable tool for research focused on bacterial infections and antibiotic development. Its specificity towards MetAP1 further positions EcMetAP1-IN-1 as a potential candidate for studying the mechanistic roles of methionine aminopeptidases in pathogenic bacteria. -
Bacterial Inhibitor
Urolithin M6 is a polyphenolic compound primarily recognized for its role as a bacterial inhibitor. This metabolite, synthesized through intestinal microbial metabolism, exhibits potential antioxidant properties and may function as an analogue to tannic acid compounds. Urolithin M6's production in humans necessitates the presence of specific bacterial 3-dehydroxylase activity, unveiling a novel pathway for its biotransformation. The metabolic profile of Urolithin M6 can aid in stratifying individuals for research aimed at elucidating its implications in health and disease. -
Bacterial Inhibitor
Methyl octanoate acts as a bacterial inhibitor and is recognized for its role in antimicrobial activity. This compound has applications in food preservation and can be studied for its effects on microbial growth inhibition. Additionally, it serves as a volatile aroma component in various beverages, including persimmon wine, making it of interest in both food science and microbiology research. -
Bacterial Inhibitor
NSC-79887 is a potent nucleoside hydrolase inhibitor that demonstrates significant activity against Bacillus anthracis. This compound serves as a promising candidate for biological testing and further development aimed at countering bacterial infections. Additionally, its pharmacokinetic profile suggests that all physicochemical parameters fall within acceptable ranges, indicating potential suitability for human use. -
Antibacterial Agent
Temafloxacin hydrochloride is an orally active quinolone that functions as a broad-spectrum antibacterial agent. This compound demonstrates significant efficacy against various bacterial strains, making it suitable for the treatment of lower respiratory and genitourinary tract infections. Temafloxacin hydrochloride's well-tolerated profile further supports its potential applications in clinical research related to bacterial infection management. -
Bacterial Inhibitor
Surgumycin is a bacterial inhibitor that exhibits notable antimicrobial activity. Its mechanism involves disrupting essential cellular processes in bacteria, making it a valuable tool for studying bacterial infections and resistance mechanisms. Surgumycin is particularly useful in research applications focused on antibiotic development and the exploration of microbial pathogenesis. -
antibacterial
Temporin-GHc is an antimicrobial peptide primarily targeting bacterial organisms. It demonstrates significant antibacterial activity with an MBIC50 value of 6 μM and exhibits antibiofilm activity with an MBEC50 value of 25 μM at 24 hours. This compound is useful for research applications focused on bacterial inhibition and biofilm formation. -
Antibacterial Agent
Moxalactam is a synthetic oxa-β-lactam antibiotic that targets bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam also effectively inhibits the production of β-lactamases, making it a valuable tool for research in antibiotic resistance and microbial pathogenesis. -
Antibacterial Agent
Antofloxacin hydrochloride is a broad-spectrum 8-amino-fluoroquinolone that functions as an antibacterial agent. It demonstrates potent activity against gyrA mutation-positive Helicobacter pylori strains, notably the Asn87 mutant, where it surpasses the efficacy of levofloxacin. Additionally, Antofloxacin hydrochloride acts as a weak, reversible inhibitor of CYP1A2, making it a valuable reagent for studying infections caused by a variety of bacterial species. -
Antibacterial Agent
Antibacterial Agent 221 is a potent inhibitor specifically targeting Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). This compound exhibits significant antibacterial activity, demonstrating effectiveness against resistant strains. Additionally, Antibacterial Agent 221 shows pronounced cytotoxicity against human LO2 and HepG2 cells, making it a valuable tool for research in antimicrobial resistance and cytotoxic effects. -
Antibacterial Agent
Nifurtoinol is a nitrofuran-derived antibiotic that exerts antibacterial activity. It is primarily investigated for its effectiveness against urinary tract infections, making it a valuable compound for research in infectious disease studies and antibiotic development. -
Bacterial Inhibitor
LL-BM123α is a bacterial inhibitor derived from Nocardia sp., with a primary mechanism of action targeting Gram-negative bacteria. This compound demonstrates moderate antimicrobial activity, making it a valuable tool in research focused on bacterial infections and antibiotic resistance. LL-BM123α can be utilized in studies aimed at understanding the efficacy of novel antibiotics and developing strategies for overcoming bacterial resistance. -
Antibacterial, Biofilm Formation Inhibitor
Majoranaquinone is a potent antibacterial agent that targets various bacterial strains, demonstrating significant inhibitory effects against four Staphylococcus species, one Moraxella species, and one Enterococcus species. Additionally, it exhibits substantial efflux pump inhibitory activity in Escherichia coli ATCC 25922. Majoranaquinone also effectively inhibits biofilm formation in both E. coli ATCC 25922 and E. coli K-12 AG100, making it a valuable reagent for research applications focused on combating bacterial infections and biofilm-related challenges. -
Antibacterial Metabolite
Monomethylsulochrin is a potent antibacterial metabolite derived from the endophytic fungus Aspergillus fumigatus, isolated from the leaves of Albizia lucidior. This compound demonstrates significant antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 31.25 μg/mL. Monomethylsulochrin serves as a valuable tool for research applications focused on exploring novel antimicrobial agents and mechanisms of bacterial resistance. -
Bacterial Inhibitor
Lauryl-LF 11 is an N-terminally acylated analogue of LF11 that acts as a bacterial inhibitor. This peptide demonstrates significant antibacterial activity, making it a valuable tool for research in microbiology and infectious diseases. It can be utilized in studies focused on the mechanisms of bacterial resistance and the development of novel antimicrobial agents. -
Antibacterial Agent
FK-041 is an orally active cephalosporin antibiotic that targets penicillin-binding proteins (PBPs) to exert its antibacterial effects. It demonstrates broad-spectrum activity against a variety of pathogens, including both Gram-positive and Gram-negative bacteria as well as anaerobes. Additionally, FK-041 shows efficacy against certain drug-resistant strains, such as penicillin-resistant Streptococcus pneumoniae. This reagent is valuable for research focused on infectious diseases and the development of new antibacterial therapies. -
Bacterial Inhibitor
Citreamicin alpha is a potent bacterial inhibitor demonstrated to exhibit significant antimicrobial activity against a range of Gram-positive cocci. In vitro studies reveal that MIC values for Staphylococci range from 0.12-4.0 μg/ml, and for Streptococcus pyogenes, they range from 0.03-0.12 μg/ml. While Citreamicin alpha shows superior efficacy compared to ampicillin, amoxicillin, and ceftriaxone, it exhibits comparable effects to vancomycin. Its effectiveness against various strains makes it a valuable reagent for research in antibiotic development and resistance studies. -
Antibacterial Agent
Ticarcillin is a semisynthetic carboxypenicillin with extended-spectrum antibacterial activity, primarily targeting bacterial cell wall synthesis. It is effective against a range of gram-positive cocci, such as streptococci and staphylococci, as well as most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin is relevant for research applications involving lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intra-abdominal infections. -
Antibacterial Agent
Cloxacillin is an orally active antibacterial agent and β-lactamase inhibitor, exhibiting an IC50 of 0.04 µM. It effectively suppresses the inflammatory response induced by Staphylococcus aureus by inhibiting the activation of mitogen-activated protein kinases (MAPKs), nuclear factor kappa B (NF-κB), and proteins associated with the NLRP3 inflammasome. This compound is useful for research applications focused on bacterial infections and inflammatory processes. -
Antibacterial/Antimalarial
1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid that exhibits antibacterial and antimalarial properties. This compound is derived from an Indonesian sponge and has potential applications in the study of infectious and tropical parasitic diseases. Its unique structural features may offer insights into the development of new therapeutic strategies against challenging pathogens. -
Antibacterial Agents
Cefetamet pivoxyl is a cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of enteropathogens, specifically Gram-negative bacteria, with the exception of Pseudomonas aeruginosa, as well as Legionella pneumophila. This compound is primarily utilized in research related to antibacterial efficacy and the development of new antimicrobial therapies. -
Antibacterial Agent
Carumonam is a sulfonated monocyclic β-lactam antibiotic that specifically targets penicillin-binding proteins (PBPs). It demonstrates potent antibacterial activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while exhibiting limited to no inhibitory effect on Streptococcus pneumoniae and Staphylococcus aureus. Additionally, Carumonam is resistant to beta-lactamase-mediated hydrolysis, making it a valuable compound for research on antibiotic resistance and infection control studies. -
Antibacterial Agent
Pseudomonic acid C is an antibacterial agent that targets bacterial cell wall synthesis through inhibition of isoleucyl-tRNA synthetase. This compound exhibits potent antibacterial activity against various Gram-positive bacteria, making it a valuable tool for research in microbiology and antibiotic development. Its mechanism offers insights into bacterial resistance and the potential for novel therapeutic strategies. -
Antibacterial Agent
Pipemidic acid trihydrate is an antibacterial agent that targets DNA gyrase to exert its effects. This compound demonstrates activity against a range of gram-negative bacteria, including Pseudomonas aeruginosa, as well as certain gram-positive bacteria. It is suitable for research focused on intestinal, urinary, and biliary tract infections, providing a valuable tool for studying bacterial resistance and therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 104 is a potent antibacterial compound primarily targeting bacterial pathogens. Demonstrating excellent in vitro antibacterial activity, it also exhibits significant efficacy in vivo against methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research focused on developing treatments for bacterial infections and studying antibiotic resistance mechanisms. -
Bacterial Inhibitor
MT0703 is an aminothiazolyl glycyl cephalosporin that targets bacterial pathogens, exhibiting potent anti-Pseudomonas activity. This compound is studied for its potential in understanding bacterial resistance mechanisms and developing novel therapeutic strategies. Its structure, featuring a 1,5-dihydroxy-4-pyridone-2-carbonyl group, enhances its efficacy against a range of bacterial infections. -
Antibacterial
GT-1 is a siderophore-linked cephalosporin with notable antibacterial activity. It demonstrates efficacy against clinically significant isolates, including Pseudomonas aeruginosa, Klebsiella oxytoca, Proteus species, Serratia marcescens, and Enterobacter aerogenes. This compound is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Antibacterial Agent
Cefroxadine is an orally active cephalosporin antibiotic that targets bacterial cell wall synthesis. It demonstrates superior antibacterial activity compared to cephalexin against Escherichia coli and Klebsiella pneumoniae, with minimum inhibitory concentration (MIC) values of 3.13 and 1.56 μg/mL, respectively. This compound is suitable for research applications focusing on bacterial infections and antibiotic resistance mechanisms. -
Antibacterial peptide
LL-37 GKE is an antibacterial peptide derived from the active domain of LL-37. It exhibits significant antibacterial activity, making it a valuable candidate for research in antibiotic development. LL-37 GKE’s properties offer potential applications in the study of infection control and the enhancement of antimicrobial therapies. -
Anti-tumor/bacterial Agent
Napyradiomycin A1 is an enantioselective compound belonging to the napyradiomycin family, characterized by its halogenated structure. This compound exhibits significant anti-tumor and antibacterial activities, making it a valuable tool in cancer research and microbiology. Its efficacy against various tumor cell lines, along with activity against select bacterial strains, positions Napyradiomycin A1 as a promising candidate for further investigation in therapeutic applications. -
ATPase/Bacterial Inhibitor
Dihydronovobiocin is a bacterial inhibitor that targets ATPase activity by binding to the GyrB subunit of DNA gyrase. This compound is useful for investigating the interactions between coumarin antibiotics, such as Novobiocin, Chlorobiocin, and Coumermycin, and their effects on DNA gyrase function. Dihydronovobiocin also has potential applications in the study of bacterial infections, facilitating research into the mechanisms of antibiotic action and resistance. -
Antibacterial Agent
Sulfaethoxypyridazine is a sulfonamide antibacterial agent that primarily targets bacterial dihydropteroate synthase, inhibiting folate synthesis. This compound exhibits significant antibacterial activity, making it effective for use in veterinary medicine as an additive in feedstuffs. Its application is centered on the prevention and treatment of bacterial infections in livestock, enhancing animal health and productivity. -
Antimalarial/Antibacterial Agent
K-41 is an orally active antibiotic derived from Streptomyces hygroscopicus. This compound exhibits significant antibacterial and antiplasmodial activities, making it a valuable tool in research focused on infectious diseases. K-41 can be utilized in studies investigating potential treatments for malaria and bacterial infections, contributing to the development of new therapeutic strategies. -
Bacterial Inhibitor
(4-Aminobenzyl)phosphonic acid is a bioactive compound that acts as a bacterial inhibitor. It exhibits notable antibacterial and potential anticancer activities, making it useful in various research applications, particularly in the synthesis of new compounds aimed at inhibiting bacterial growth. Its unique structural properties enable effective interaction with biological targets, facilitating the exploration of novel therapeutic strategies. -
Antibacterial Agent
Mupirocin calcium is an orally active antibacterial agent derived from Pseudomonas fluorescens. It primarily functions by reversibly inhibiting isoleucyl-transfer RNA, which disrupts bacterial protein and RNA synthesis, leading to effective antimicrobial activity. This compound is utilized in research applications aimed at studying bacterial resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
MGB-BP-3 is a bacterial inhibitor that targets multi-resistant Gram-positive pathogens. This antibiotic exhibits potent activity across a variety of clinically relevant bacterial strains, making it a valuable tool for studies focused on combating antibiotic resistance. Its broad-spectrum efficacy supports research applications in antibiotic development and microbiology. -
Antibacterial Agent
Valnemulin is a broad-spectrum antibacterial agent with efficacy against both Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria, Mycoplasma, and Spirochetes. It is primarily utilized in veterinary medicine to treat enteric diseases, acute polyarthritis, and enzootic pneumonia in swine. Additionally, Valnemulin demonstrates anti-inflammatory properties, effectively mitigating lipopolysaccharide-induced lung injury in experimental models. -
Antibacterial Agent
Altromycin D is an antibiotic primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on the study of bacterial resistance and the development of new antimicrobial therapies. Its specific mechanism of action contributes to its efficacy in inhibiting the growth of pathogenic bacteria. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Antibacterial Agent
Antofloxacin is a potent, orally active broad-spectrum 8-amino-fluoroquinolone that serves as an antibacterial agent. It exhibits enhanced activity against gyrA mutation-positive Helicobacter pylori strains, particularly those with Asn87 mutations, outperforming levofloxacin. Additionally, Antofloxacin acts as a weak, reversible inhibitor of CYP1A2, making it a valuable tool for the study of infections caused by various bacterial species. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
Recombinant Bacterial Clones Chromogenic Substrate
X-GalNAc is a chromogenic substrate that specifically targets N-acetyl-β-galactosidase. This reagent is utilized in molecular biology to detect the presence of cloned DNA inserts in bacterial colonies cultured on agar plates. The enzymatic hydrolysis of X-GalNAc results in a distinct color change, facilitating easy identification of recombinant bacterial clones in various genetic research applications. -
Bacterial Inhibitor
Resazurin sodium is a non-toxic, stable redox indicator that targets bacterial activity through its membrane-permeable properties. It serves as a vital tool for assessing cell viability, proliferation, and toxicity in various cell types, including human, plant, animal, bacterial, and fungal cells. Upon reduction, Resazurin sodium transforms into Resorufin, a highly fluorescent compound, enabling sensitive detection and quantification of cellular processes under fluorescent microscopy or spectrophotometry. -
Antibacterial Agent
ANS ammonium is a potent antibacterial agent that also serves as a textile dye. It functions as a fluorescence probe, enabling the detection of various biological interactions. Additionally, ANS ammonium is known to inhibit the binding of triiodothyronine to thyroxine binding globulin, making it useful in radioimmunoassays for triiodothyronine analysis. -
Bacterial Inhibitor
4-Methylherniarin, a coumarin derivative, exhibits antibacterial activity by effectively inhibiting both gram-positive and gram-negative bacterial strains. It demonstrates significant antimicrobial efficacy against B. subtilis and S. sonnei, with IC50 values of 11.76 μg/ml and 13.47 μg/ml, respectively. This compound serves as a valuable tool for research applications focused on combating bacterial infections and elucidating mechanisms of action in microbial resistance. -
Bacterial Inhibitor
Procodazole is a potent bacterial inhibitor that enhances immune response, offering protection against various viral and bacterial infections. In addition to its broad-spectrum antibacterial effects, Procodazole demonstrates antiparasitic activity and serves as a carbonic anhydrase inhibitor, contributing to its antitumor properties. This compound is suitable for research applications focused on infectious diseases and cancer biology. -
Bacterial Inhibitor
Aniline-MPB-amino-C3-PBD is a cytotoxic agent targeting bacterial cells through minor-groove binding of DNA. This sequence-selective compound serves as an effective payload for antibody-drug conjugates (ADCs), enhancing their therapeutic efficacy. Its antimicrobial properties make it a valuable tool for research in bacterial inhibition and related applications.
