Biological Activity
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 56.76 mL | 283.8 mL | 567.6 mL |
0.5 mM | 11.35 mL | 56.76 mL | 113.52 mL |
1 mM | 5.68 mL | 28.38 mL | 56.76 mL |
5 mM | 1.14 mL | 5.68 mL | 11.35 mL |
*The above data is based on the productmolecular weight 176.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A22008 |
---|---|
Actions | Agonist |
M. Wt | 176.18 |
Formula | C7H8N6 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 851776-28-8 |
Synonyms | mk0354, mk 0354 |
SMILES | C12=C(CCC2)C(C3=NN=NN3)=NN1 |
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