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Biological Activity
MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
| In vitro | DMSO | Warmed: 87 mg/mL | |
| Water | 87 mg/mL | ||
| Ethanol | 87 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.52 mL | 107.62 mL | 215.24 mL |
| 0.5 mM | 4.3 mL | 21.52 mL | 43.05 mL |
| 1 mM | 2.15 mL | 10.76 mL | 21.52 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 464.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11485 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1190378-57-4 |
| Formula | C26H36N6O2 |
| M. Wt | 464.6 |
| Purity | >98% |
| Synonyms | MRT 67307, MRT-67307 |
| SMILES | C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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