MS-275 (Entinostat)

Catalog No.: A10611

HDAC inhibitor

MS-275 (Entinostat)

MS-275 (Entinostat) Chemical Structure

CAS NO. 209783-80-2

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $70.00

Special Price $56.00

50 mg

Regular Price: $90.00

Special Price $72.00

200 mg

Regular Price: $190.00

Special Price $152.00

10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.
Targets
HDAC1 (Cell-free assay) HDAC3 (Cell-free assay)
0.51 μM1.7 μM
In vitro (25°C) DMSO 75 mg/mL (199.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.57 mL 132.84 mL 265.67 mL
0.5 mM 5.31 mL 26.57 mL 53.13 mL
1 mM 2.66 mL 13.28 mL 26.57 mL
5 mM 0.53 mL 2.66 mL 5.31 mL

*The above data is based on the productmolecular weight 376.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10611
Actions Inhibitor
M. Wt 376.4
Formula C21H20N4O3
Solubility DMSO>75mg/mL Water<1mg/mL Ethanol<1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 209783-80-2
Synonyms SNDX-275
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3

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