MS-275 (Entinostat)

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$35.00
In stock
25mg
$65.00
In stock
50mg
$85.00
In stock
100mg
$120.00
In stock
200mg
$185.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Adooq's MS-275 (Entinostat) has been cited by 6 publications
  • Wenguang Liu, .et al. , Biochem Biophys Res Commun, 2024, Dec 20:739:150970 PMID: 39550862
  • Vivek Bora, .et al. , Can J Physiol Pharmacol, 2021, 6 October
  • Taito Kashio, .et al. , Tissue Barriers, 2021, May 6;1911195 PMID: 33955828
  • Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
  • Arshdeep Singh, .et al. , Eur J Med Chem, 2021, Apr 5;215:113169 PMID: 33588178
  • Minoru Ueda, .et al. , Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096
  • Biological Activity
    Discription MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10611
    Formula C21H20N4O3
    Molecular Weight 376.4
    CAS Number 209783-80-2
    SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
    Synonyms SNDX-275
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 71 mg/mL (188.62 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.57 mL 132.84 mL 265.67 mL
    0.5 mM 5.31 mL 26.57 mL 53.13 mL
    1 mM 2.66 mL 13.28 mL 26.57 mL
    5 mM 0.53 mL 2.66 mL 5.31 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy MS-275 (Entinostat) | MS-275 (Entinostat) Supplier | purchase MS-275 (Entinostat) | MS-275 (Entinostat) cost | MS-275 (Entinostat) manufacturer | order MS-275 (Entinostat) | MS-275 (Entinostat) distributor | buy 209783-80-2 | 209783-80-2 Supplier | purchase 209783-80-2 | 209783-80-2 cost | 209783-80-2 manufacturer | order 209783-80-2 | 209783-80-2 distributor