MS-275 (Entinostat)

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.
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Product Name Price Stock Qty
MS-275 10mg
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MS-275 25mg
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MS-275 50mg
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MS-275 200mg
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MS-275 (Entinostat) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's MS-275 (Entinostat) has been cited by 5 publications
  • Vivek Bora, .et al. , Can J Physiol Pharmacol, 2021, 6 October
  • Taito Kashio, .et al. , Tissue Barriers, 2021, May 6;1911195 PMID: 33955828
  • Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
  • Arshdeep Singh, .et al. , Eur J Med Chem, 2021, Apr 5;215:113169 PMID: 33588178
  • Minoru Ueda, .et al. , Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096
  • Biological Activity
    Discription MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.
    Target Value
    Product Information
    Catalog Num A10611
    Formula C21H20N4O3
    Molecular Weight 376.4
    CAS Number 209783-80-2
    Synonyms SNDX-275

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 71 mg/mL (188.62 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.57 mL 132.84 mL 265.67 mL
    0.5 mM 5.31 mL 26.57 mL 53.13 mL
    1 mM 2.66 mL 13.28 mL 26.57 mL
    5 mM 0.53 mL 2.66 mL 5.31 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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