MSA-2 dimer is a selective, orally active non-nucleotide STING agonist that demonstrates a binding affinity (Kd) of 145 μM. This compound promotes long-term antitumor effects and enhances immunogenic activity by non-covalently interacting with STING in a dimeric form, offering superior permeability compared to cyclic dinucleotides. MSA-2 dimer is particularly valuable for research into cancer immunotherapy and the modulation of innate immune responses.
MSA-2 dimer is a selective, orally active non-nucleotide STING agonist that demonstrates a binding affinity (Kd) of 145 μM. This compound promotes long-term antitumor effects and enhances immunogenic activity by non-covalently interacting with STING in a dimeric form, offering superior permeability compared to cyclic dinucleotides. MSA-2 dimer is particularly valuable for research into cancer immunotherapy and the modulation of innate immune responses.
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