MSX-122

Catalog No.: A12596

CXCR4 Inhibitor

MSX-122

MSX-122 Chemical Structure

CAS NO. 897657-95-3

MSX-122 is an orally bioavailable inhibitor of CXCR4 (IC50 = ~10 nM) with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$320.00
100 mg
$550.00
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Biological Activity

MSX-122 is an orally bioavailable inhibitor of CXCR4 (IC50 = ~10 nM) with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration.
In vitro DMSO 3 mg/mL (10.26 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.21 mL 171.03 mL 342.07 mL
0.5 mM 6.84 mL 34.21 mL 68.41 mL
1 mM 3.42 mL 17.1 mL 34.21 mL
5 mM 0.68 mL 3.42 mL 6.84 mL

*The above data is based on the productmolecular weight 292.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12596
Actions Inhibitor
CAS No. 897657-95-3
Formula C16H16N6
M. Wt 292.34
Solubility DMSO
Purity >98%
Synonyms MSX122, MSX 122
SMILES C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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