Murepavadin

Name: Murepavadin
Brand: Adooq Bioscience
SKU: A47577
Rating: 5 (288 reviews)

Catalog No.: A47577

Antibiotic

Murepavadin is a 14-amino-acid cyclic peptide targeting lipopolysaccharide transport protein D, demonstrating potent antibiotic activity against Pseudomonas aeruginosa. With MIC50 and MIC90 values of 0.12 mg/L, Murepavadin is effective in combating this opportunistic pathogen. This compound is valuable for research into bacterial resistance mechanisms and the development of new therapeutic strategies.

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Biological Activity

Description

Product Information

Catalog Num	A47577
Formula	C73H112N22O16
Molecular Weight	1553.81
CAS Number	944252-63-5
Sequence	Cyclo(Ala-Ser-{d-Pro}-Pro-Thr-Trp-Ile-{Dab}-{Orn}-{d-Dab}-{Dab}-Trp-{Dab}-{Dab})
Sequence shortening	Cyclo(AS-{d-Pro}-PTWI-{Dab}-{Orn}-{d-Dab}-{Dab}-W-{Dab}-{Dab})
SMILES	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCN)NC(=O)[C@@H](CCN)NC(=O)[C@H](CCCN)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O
Synonyms	POL7080

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