MY-1B

Name: MY-1B
Brand: Adooq Bioscience
SKU: A24365
Rating: 5 (288 reviews)

Catalog No.: A24365

NSUN2 inhibitor

MY-1B is a covalent inhibitor of the RNA methyltransferase NSUN2 (IC50: 1.3 μM), stereoselectively targeting active-site cysteine residues (C271). It also covalently binds to PSME1, disrupting the proteasome regulatory complex and downregulating specific MHC-I subtype presentation.

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Grouped product items
Size	Price	Stock
5mg	$315.00	In stock
10mg	$543.00	In stock
50mg	$1,610.00	In stock
100mg	$3,150.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description	MY-1B is a covalent inhibitor of the RNA methyltransferase NSUN2 (IC50: 1.3 μM), stereoselectively targeting active-site cysteine residues (C271). It also covalently binds to PSME1, disrupting the proteasome regulatory complex and downregulating specific MHC-I subtype presentation.

Product Information

Catalog Num	A24365
Formula	C22H18BrN3O2
Molecular Weight	436.30
CAS Number	2929308-79-0
SMILES	O=C([C@H]1[C@@H](C2=CC=C(C=C2)Br)CN1C(C=C)=O)NC3=CC=CC4=C3N=CC=C4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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