Mycophenolate mofetil (CellCept)

Catalog No.: A10613

IMPDH inhibitor

Mycophenolate mofetil (CellCept)

Mycophenolate mofetil (CellCept) Chemical Structure

CAS NO. 128794-94-5

Mycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells.

Availability: In stock

Package Price Qty
50 mg
$50.00
200 mg
$100.00
500 mg
$200.00
10mM * 1mL in DMSO
$63.00
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Biological Activity

Mycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells.
Targets
Inosine monophosphate dehydrogenase II Inosine monophosphate dehydrogenase I
27 nM39 nM
In vitro (25°C) DMSO 77 mg/mL (177.62 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% methylcellulose 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.07 mL 115.34 mL 230.68 mL
0.5 mM 4.61 mL 23.07 mL 46.14 mL
1 mM 2.31 mL 11.53 mL 23.07 mL
5 mM 0.46 mL 2.31 mL 4.61 mL

*The above data is based on the productmolecular weight 433.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10613
Actions Inhibitor
CAS No. 128794-94-5
Formula C23H31NO7
M. Wt 433.5
Purity >98%
Synonyms CellCept, RS 61443, TM-MMF
SMILES CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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