(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid, with notable antibacterial and antifungal properties. It demonstrates activity against Gram-positive bacteria, including Bacillus subtilis, Kocuria rhizophila, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 4, 8, and 4 µg/mL, respectively. In contrast, it exhibits limited effectiveness against Gram-negative bacteria such as Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. Additionally, (–)-Mycousnine is effective against fungi, including Trichophyton mentagrophytes, Trichophyton rubrum, and Candida albicans, with MICs of 25, 25, and 100 µg/mL, respectively. This compound is suitable for research in antimicrobial drug development and fungal infection studies.
(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid, with notable antibacterial and antifungal properties. It demonstrates activity against Gram-positive bacteria, including Bacillus subtilis, Kocuria rhizophila, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 4, 8, and 4 µg/mL, respectively. In contrast, it exhibits limited effectiveness against Gram-negative bacteria such as Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. Additionally, (–)-Mycousnine is effective against fungi, including Trichophyton mentagrophytes, Trichophyton rubrum, and Candida albicans, with MICs of 25, 25, and 100 µg/mL, respectively. This compound is suitable for research in antimicrobial drug development and fungal infection studies.
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