N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile tool for targeted protein degradation research applications.
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile tool for targeted protein degradation research applications.
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