N-PEG3-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, this linker can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool in chemical biology and drug development research. Its application in PROTAC technology supports studies targeting protein degradation pathways for therapeutic discovery.
N-PEG3-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, this linker can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool in chemical biology and drug development research. Its application in PROTAC technology supports studies targeting protein degradation pathways for therapeutic discovery.
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