N-Pentanoyl 2-benzyltryptamine is a selective antagonist of the MT2 melatonin receptor, exhibiting a pKi of 8.03 for human MT2. This compound demonstrates significant selectivity, with 89-fold and 229-fold preference for human MT2 over human MT1 and Xenopus mel1c receptor subtypes, respectively. N-Pentanoyl 2-benzyltryptamine effectively inhibits melatonin-induced enhancement of electrically-evoked responses, making it a valuable tool for research in circadian rhythms and melatonin signaling pathways.
N-Pentanoyl 2-benzyltryptamine is a selective antagonist of the MT2 melatonin receptor, exhibiting a pKi of 8.03 for human MT2. This compound demonstrates significant selectivity, with 89-fold and 229-fold preference for human MT2 over human MT1 and Xenopus mel1c receptor subtypes, respectively. N-Pentanoyl 2-benzyltryptamine effectively inhibits melatonin-induced enhancement of electrically-evoked responses, making it a valuable tool for research in circadian rhythms and melatonin signaling pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
