N3-PEG3-CH2CH2-Boc is a cleavable linker designed for use in PROTAC synthesis, specifically serving as a 3-unit polyethylene glycol (PEG) intermediary. This compound facilitates the formation of antibody-drug conjugates (ADCs) and supports click chemistry applications through its azide group. It readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-functionalized molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, proving valuable in diverse chemical research applications.
N3-PEG3-CH2CH2-Boc is a cleavable linker designed for use in PROTAC synthesis, specifically serving as a 3-unit polyethylene glycol (PEG) intermediary. This compound facilitates the formation of antibody-drug conjugates (ADCs) and supports click chemistry applications through its azide group. It readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-functionalized molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, proving valuable in diverse chemical research applications.
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