Neothramycin A

Catalog No.: A27547
Antibiotic
Neothramycin A is an antibiotic derived from the Streptomyces genus, targeting a broad spectrum of microbial organisms. It demonstrates significant antimicrobial activity against Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) ranging from 25 to 50 μg/mL. Additionally, Neothramycin A exhibits antitumor properties in preclinical models, particularly against leukemia, highlighting its potential for further research in both infectious diseases and cancer therapeutics.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNeothramycin A is an antibiotic derived from the Streptomyces genus, targeting a broad spectrum of microbial organisms. It demonstrates significant antimicrobial activity against Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) ranging from 25 to 50 μg/mL. Additionally, Neothramycin A exhibits antitumor properties in preclinical models, particularly against leukemia, highlighting its potential for further research in both infectious diseases and cancer therapeutics.
Product Information
Catalog NumA27547
FormulaC13H14N2O4
Molecular Weight262.26
CAS Number59593-16-7
SMILESO=C1C2=CC(OC)=C(O)C=C2N=C[C@@]3([H])N1[C@H](CC3)O
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