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Nexturastat A

Catalog No.: A14032

HDAC6 inhibitor

Nexturastat A

Nexturastat A Chemical Structure

CAS NO. 1403783-31-2

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM).

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$350.00
10mM * 1mL in DMSO
$80.00
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Biological Activity

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM).
Targets
HDAC6
5 nM
In vitro DMSO 59 mg/mL (172.81 mM)
Water Insoluble
Ethanol 2 mg/mL (5.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.29 mL 146.45 mL 292.91 mL
0.5 mM 5.86 mL 29.29 mL 58.58 mL
1 mM 2.93 mL 14.65 mL 29.29 mL
5 mM 0.59 mL 2.93 mL 5.86 mL

*The above data is based on the productmolecular weight 341.40422. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14032
Actions Inhibitor
CAS No. 1403783-31-2
Formula C19H23N3O3
M. Wt 341.40422
Purity >98%
Synonyms Nexturastat-A,NexturastatA
SMILES CCCCN(CC1=CC=C(C=C1)C(=O)NO)C(=O)NC2=CC=CC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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