NF023 hexasodium is a selective and competitive antagonist of the P2X1 receptor, demonstrating an IC50 value of 0.21 μM. While showing significantly higher IC50 values of 28.9 μM, > 50 μM, and > 100 μM for human P2X3, P2X2, and P2X4 receptor-mediated responses respectively, it provides a robust tool for investigating P2X1 receptor functions. This reagent is valuable in pharmacological research and studies exploring the role of purinergic signaling in various physiological and pathological processes.
NF023 hexasodium is a selective and competitive antagonist of the P2X1 receptor, demonstrating an IC50 value of 0.21 μM. While showing significantly higher IC50 values of 28.9 μM, > 50 μM, and > 100 μM for human P2X3, P2X2, and P2X4 receptor-mediated responses respectively, it provides a robust tool for investigating P2X1 receptor functions. This reagent is valuable in pharmacological research and studies exploring the role of purinergic signaling in various physiological and pathological processes.
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