NH-bis(C2-PEG1-azide) is a versatile PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This compound is essential for developing targeted protein degradation strategies and is widely applicable in chemical biology and drug discovery research.
NH-bis(C2-PEG1-azide) is a versatile PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This compound is essential for developing targeted protein degradation strategies and is widely applicable in chemical biology and drug discovery research.
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