Nimustine Hydrochloride

Catalog No.: A17583

Nimustine Hydrochloride

Nimustine Hydrochloride Chemical Structure

CAS NO. 55661-38-6

Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$70.00
50 mg
$220.00
100 mg
$400.00
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Biological Activity

Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.
In vitro DMSO 60 mg/mL (194.08 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.35 mL 161.73 mL 323.47 mL
0.5 mM 6.47 mL 32.35 mL 64.69 mL
1 mM 3.23 mL 16.17 mL 32.35 mL
5 mM 0.65 mL 3.23 mL 6.47 mL

*The above data is based on the productmolecular weight 309.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17583
CAS No. 55661-38-6
Formula C9H14Cl2N6O2
M. Wt 309.15
Purity >98%
Synonyms CS 439 HCl; CS439 HCl; CS-439 HCl; CS-439; CS439; CS 439
SMILES O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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