Biological Activity
Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 32.35 mL | 161.73 mL | 323.47 mL |
0.5 mM | 6.47 mL | 32.35 mL | 64.69 mL |
1 mM | 3.23 mL | 16.17 mL | 32.35 mL |
5 mM | 0.65 mL | 3.23 mL | 6.47 mL |
*The above data is based on the productmolecular weight 309.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17583 |
---|---|
M. Wt | 309.15 |
Formula | C9H14Cl2N6O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 55661-38-6 |
Synonyms | CS 439 HCl; CS439 HCl; CS-439 HCl; CS-439; CS439; CS 439 |
SMILES | O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O.[H]Cl |
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