Ilginatinib (NS-018) maleate
Catalog No.: A16226
JAK2 inhibitor
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Research use only. We do not sell to patients.
Other Forms of Ilginatinib (NS-018) maleate
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| Description | NS-018 maleate is an ATP-competitive small-molecule inhibitor of JAK2 with IC50 of 470nM in Ba/F3-JAK2V617F cells . have30-50-fold greater selectivity for JAK2 over other JAK-family kinases, such as JAK1, JAK3 and tyrosine kinase 2. | ||
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| Catalog Num | A16226 |
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| Formula | C25H24FN7O4 |
| Molecular Weight | 505.5 |
| CAS Number | 1354799-87-3 |
| SMILES | CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.C(=CC(=O)O)C(=O)O |
| Synonyms | NS018 maleate, NS 018 maleate |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
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