NS-018

Catalog No.: A16224

JAK2 inhibitor

NS-018

NS-018 Chemical Structure

CAS NO. 1239358-86-1

NS-018 is an orally bioavailable, small molecule inhibitor of Janus-associated kinase 2 (JAK2) and Src-family kinases, with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $320.00

Special Price $256.00

10 mg

Regular Price: $480.00

Special Price $384.00

50 mg

Regular Price: $1,400.00

Special Price $1,120.00

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Biological Activity

NS-018 is an orally bioavailable, small molecule inhibitor of Janus-associated kinase 2 (JAK2) and Src-family kinases, with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.39 mL 256.79 mL
0.5 mM 5.14 mL 25.68 mL 51.36 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16224
Actions Inhibitor
CAS No. 1239358-86-1
Formula C21H20FN7
M. Wt 389.43
Purity >98%
Synonyms NS018, NS 018
SMILES CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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