NT376 is a potent and selective inhibitor of class-IIa Histone deacetylases (HDAC), demonstrating an IC50 value of 32 nM in HT-29 cells. It exhibits significant biological activity that supports its role in cancer research and the investigation of central nervous system disorders, including Alzheimer's and Huntington's diseases. NT376 serves as a valuable tool for studying the epigenetic regulation of gene expression and potential therapeutic pathways in these conditions.
NT376 is a potent and selective inhibitor of class-IIa Histone deacetylases (HDAC), demonstrating an IC50 value of 32 nM in HT-29 cells. It exhibits significant biological activity that supports its role in cancer research and the investigation of central nervous system disorders, including Alzheimer's and Huntington's diseases. NT376 serves as a valuable tool for studying the epigenetic regulation of gene expression and potential therapeutic pathways in these conditions.
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