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Nystatin A1

Catalog No.: A27354
Antibiotic
Nystatin A1 is a polyene macrolide antifungal antibiotic derived from Streptomyces noursei. It selectively binds to ergosterol in the fungal cell membrane, resulting in increased membrane permeability and the subsequent leakage of cellular contents. This mechanism effectively inhibits the growth and reproduction of various fungi, making Nystatin A1 an important reagent for antifungal research and studies involving fungal infections.
Nystatin A1 34786-70-4 Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNystatin A1 is a polyene macrolide antifungal antibiotic derived from Streptomyces noursei. It selectively binds to ergosterol in the fungal cell membrane, resulting in increased membrane permeability and the subsequent leakage of cellular contents. This mechanism effectively inhibits the growth and reproduction of various fungi, making Nystatin A1 an important reagent for antifungal research and studies involving fungal infections.
Product Information
Catalog NumA27354
FormulaC47H75NO17
Molecular Weight926.09
CAS Number34786-70-4
SMILESO=C([C@H]1[C@]2([H])C[C@@H](O[C@H]3[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O3)/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O2)(O)C[C@@H]1O)=O)O
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Microbiology > Antifection > Antibiotic