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Odanacatib (MK-0822)

Catalog No.: A11265

Cathepsin K Inhibitor

Odanacatib (MK-0822)

Odanacatib (MK-0822) Chemical Structure

CAS NO. 603139-19-1

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.

Availability: In stock

Package Price Qty
5 mg
10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Biological Activity

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
Cathepsin K (human) Cathepsin K (rabbit)
0.2 nM1 nM
In vitro (25°C) DMSO 96 mg/mL (182.66 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.13 mL 190.26 mL
0.5 mM 3.81 mL 19.03 mL 38.05 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11265
Actions Inhibitor
CAS No. 603139-19-1
Formula C25H27F4N3O3S
M. Wt 525.6
Purity >98%
Synonyms MK0822
SMILES CC(C)(C[C@@H](C(=O)NC1(CC1)C#N)N[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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