Oligomycin C

Catalog No.: A28185
Macrolide Antibiotic
Oligomycin C is a macrolide antibiotic that specifically inhibits ATP synthase, thereby disrupting mitochondrial function. This compound demonstrates potent antifungal activity against a range of pathogens, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, making it a valuable tool for studying fungal infections and mitochondrial bioenergetics. Its selective action on fungi, with no antibacterial activity, further emphasizes its utility in antifungal research applications.
Grouped product items
Size Price Stock Qty
1mg
$685.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOligomycin C is a macrolide antibiotic that specifically inhibits ATP synthase, thereby disrupting mitochondrial function. This compound demonstrates potent antifungal activity against a range of pathogens, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, making it a valuable tool for studying fungal infections and mitochondrial bioenergetics. Its selective action on fungi, with no antibacterial activity, further emphasizes its utility in antifungal research applications.
Product Information
Catalog NumA28185
FormulaC45H74O10
Molecular Weight775.06
CAS Number11052-72-5
SMILESO=C([C@@H]([C@H]([C@@H](C([C@H]([C@H]([C@@H](C/C=C/C=C/[C@@]([H])(CC[C@]1([C@H]([C@@]([H])(O2)[C@@H]([C@]3(O1)CC[C@@H]([C@@]([H])(O3)C[C@@H](C)O)C)C)C)[H])CC)C)O)C)=O)C)O)C)[C@H]([C@@H]([C@H](/C=C/C2=O)C)O)C
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