OSU-T315

Catalog No.: A20870

ILK inhibitor

OSU-T315

OSU-T315 Chemical Structure

CAS NO. 2070015-22-2

OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain).

Availability: In stock

Package Price Qty
2 mg
$216.00
5 mg
$432.00
10 mg
$840.00
50 mg
$2,472.00
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Biological Activity

OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain).
In vitro DMSO 91 mg/mL (170.53 mM)
Water <1 mg/mL
Ethanol 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.74 mL 93.7 mL 187.41 mL
0.5 mM 3.75 mL 18.74 mL 37.48 mL
1 mM 1.87 mL 9.37 mL 18.74 mL
5 mM 0.37 mL 1.87 mL 3.75 mL

*The above data is based on the productmolecular weight 533.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20870
Actions Inhibitor
CAS No. 2070015-22-2
Formula C30H30F3N5O
M. Wt 533.59
Purity >98%
Synonyms OSUT315, OSU T315
SMILES O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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