Catalog No.
Product Name
Application
Product Information
Citations
-
Drug Impurity
Clozapine impurity 8 is a known impurity of the atypical antipsychotic clozapine, primarily identified for its role in therapeutic formulations. This compound is essential for assessing the quality and safety of clozapine, aiding in the understanding of its metabolic profile and overall pharmacological impact. Researchers can utilize this impurity in drug development and analytical studies to ensure compliance with regulatory standards for pharmaceutical products. -
Drug Intermediate
4,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine is a versatile drug intermediate utilized in the synthesis of various bioactive compounds. This compound facilitates the development of novel pharmaceuticals, playing a critical role in medicinal chemistry research. Its significant chemical structure allows researchers to explore a range of therapeutic applications, making it an essential reagent in the drug discovery process. -
Drug Intermediate
(5-Methyl-1-Tritylimidazol-4-yl)Methanol is a versatile drug intermediate utilized in the synthesis of various bioactive compounds. This compound plays a pivotal role in the development of pharmaceuticals, facilitating the formation of complex structures required for medicinal chemistry research. Its unique imidazole core and trityl group enhance reactivity and serve as essential building blocks in drug design. -
Drug Impurity
Tofacitinib impurity 6 is a chemical impurity associated with Tofacitinib, a selective Janus kinase (JAK) inhibitor. It is primarily used to support analytical evaluations and quality control in pharmaceutical research involving Tofacitinib. This compound is essential for the identification and quantification of impurities, facilitating the maintenance of drug safety and efficacy standards. -
Drug Impurity
Sildenafil Impurity 1 is a known impurity of the phosphodiesterase type 5 inhibitor, Sildenafil. Characterized for its relevance in pharmacological studies, this compound serves as a critical reference standard for quality control in the synthesis and analysis of Sildenafil. Its identification and quantification are essential in ensuring the purity and safety of pharmaceutical formulations containing Sildenafil. -
Drug Intermediate
2-Chloro-4-methyl-3-nitropyridine is a versatile pyridine derivative primarily utilized as a drug intermediate. It serves as a crucial building block in the synthesis of 2-methoxypyridine derivatives, which exhibit significant antibacterial and antituberculosis activities. This compound is valuable in medicinal chemistry for the development of new therapeutic agents targeting microbial infections. -
Drug Intermediate
Desmethyl nevanimibe is a drug intermediate and a demethyl precursor of the sterol O-acyltransferase 1 (SOAT1) inhibitor Nevanimibe (PD-132301). This compound plays a critical role in the synthesis of SOAT1 inhibitors, which are of interest in the study of lipid metabolism and associated diseases. Research applications include investigations into cholesterol metabolism and the potential therapeutic effects in treating metabolic disorders. -
Drug Intermediate
2-Bromo-3-methylpyridine is a heterocyclic compound that serves as a halomethylpyridine intermediate. This reagent is primarily utilized in the synthesis of platinum(IV) diazide complexes, offering valuable applications in drug discovery and development. Its structural features enable its role in further synthetic pathways, particularly in the creation of novel pharmaceuticals. -
Drug Intermediate
7-Aminodeacetoxycephalosporanic acid (7-ADCA) serves as a crucial intermediate in the synthesis of cephalosporin antibiotics. Its structure is essential for the development of various cephalosporin derivatives, which exhibit broad-spectrum antibacterial activity. 7-ADCA is widely utilized in pharmaceutical research and development for the formulation of novel antimicrobial agents. -
Drug Intermediate
2,4-Dibromo-5-nitropyridine is a trisubstituted pyridine derivative primarily utilized as a drug intermediate. This compound plays a crucial role in the synthesis of Rho kinase inhibitors, which are important in the study of various cellular processes and disease pathways, including cancer and cardiovascular disorders. Its reactivity and structural features make it valuable for research applications focused on the modulation of Rho kinase activity. -
Drug Intermediate
5-Bromo-3-fluoropicolinic acid is a key intermediate in the synthesis of pharmaceutical compounds, specifically used in the development of inhibitors targeting glycinamide ribonucleotide formyltransferase. This compound serves as a valuable building block in medicinal chemistry, facilitating the exploration of novel therapeutic agents. Its specific structural features support research applications in drug discovery and development. -
Drug Impurity
Paliperidone impurity 15 is a chemical impurity associated with the antipsychotic agent paliperidone. This impurity serves as a key component for studies focused on the characterization and analysis of pharmaceutical formulations. It is essential for quality control and regulatory compliance in the production of paliperidone and may be utilized in analytical research to elucidate the compound's purity profile. -
Drug Intermediate
4-Bromo-3-fluorobenzaldehyde is an important drug intermediate characterized by its role in the synthesis of triaryl dimer antibacterial compounds. This compound serves as a valuable building block in drug discovery and development, aiding researchers in the design of novel antibacterial agents. Its unique chemical structure makes it suitable for various applications in medicinal chemistry. -
Drug Intermediate
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a key drug intermediate in the synthesis of Tirzepatide, which functions as a dual agonist of the glucose-dependent insulinotropic peptide (GIP) and the glucagon-like peptide-1 receptor (GLP-1R). This compound is essential for research and development in diabetes therapeutics, as Tirzepatide enhances insulin secretion and improves glycemic control. Its structural features facilitate the exploration of peptide-based treatments for metabolic disorders. -
Drug Intermediate
GGFG-Exatecan TFA is a synthetic drug intermediate designed for use in antibody-drug conjugates (ADCs). This compound features a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker conjugated to Exatecan, a DNA topoisomerase I inhibitor. It plays a critical role in cancer research, facilitating the development of targeted therapeutic strategies. -
Drug Intermediate
2,2-Diethoxyethanol functions as a drug intermediate, particularly in the synthesis of pharmaceutical compounds. Its utility is notable in research focused on the treatment of Plasmodium falciparum infections, contributing to the development of potential antimalarial therapies. Researchers may leverage this compound to explore its efficacy and mechanisms within related biological assays. -
Drug Intermediate
17-Hydroxypregnenolone sulfate sodium is a crucial intermediate involved in adrenal and gonadal steroidogenesis. It serves as a precursor in the biosynthesis of various steroid hormones, including glucocorticoids and sex hormones. This compound is significant for research related to adrenal function development and has potential applications in studying neurosteroid-related diseases such as cognitive impairment and neurodegenerative disorders. -
Drug Intermediate
2-Bromo-3-methoxypyridine serves as a versatile drug intermediate, primarily utilized in the synthesis of the metabolite of Piroxicam. This compound is integral for researchers involved in pharmacological studies and the development of anti-inflammatory therapeutics. Its structural properties facilitate various chemical reactions, making it a valuable asset in drug discovery and development processes. -
Drug Impurity
Candesartan impurity 26 is a known impurity of the angiotensin II receptor blocker, Candesartan. Its presence is significant in the analysis of pharmaceutical formulations and quality control processes. This compound is essential for researchers conducting stability studies, impurity profiling, and regulatory compliance in drug development. -
Drug Intermediate
(1S,2S)-2-((R)-1-Phenylethylamino)cyclohexanol serves as an important drug intermediate in the synthesis of diverse active pharmaceutical ingredients. This compound is employed in medicinal chemistry to facilitate the development of novel therapeutic agents. Its structural characteristics make it a valuable building block for further chemical transformations and applications in drug discovery. -
Drug Intermediate Control
tert-Butyl 1H-indol-4-ylcarbamate serves as a synthetic intermediate commonly employed in pharmaceutical synthesis. Its structure facilitates various chemical transformations, making it significant for the development of indole-based therapeutics. This compound is integral for researchers focusing on drug discovery and development processes. -
Drug Intermediate
3-Chloro-2,4,5-trifluoro-6-nitrobenzoic acid serves as a key drug intermediate in the synthesis of a variety of active pharmaceutical compounds. Its unique chemical structure allows for versatile applications in medicinal chemistry, facilitating the development of novel therapeutic agents. This compound is essential for researchers involved in drug design and synthesis. -
Drug Impurity
Ethinylestradiol impurity 3 is a known impurity associated with the synthesis of Ethinylestradiol, a synthetic estrogen used in various hormonal therapies. This compound can be utilized in quality control and analytical studies to evaluate the purity of Ethinylestradiol formulations. Its presence in pharmaceutical preparations can affect the efficacy and safety profiles of estrogenic treatments, making it relevant in drug development and regulatory assessments. -
Drug Impurity
Apixaban impurity 46 is a characterized impurity associated with the anticoagulant Apixaban. This compound is crucial for the quality control and validation processes in pharmaceutical research, aiding in the assessment of drug purity and stability. Its analysis is essential for ensuring compliance with regulatory standards in drug development and manufacturing, ultimately contributing to safer therapeutic applications. -
Drug Intermediate
3-(3,5-Dichlorophenyl)-1-methylhydantoin is a versatile drug intermediate utilized in the synthesis of various bioactive compounds. This compound serves as a building block in pharmaceutical research, facilitating the development of novel therapeutics. Its unique chemical structure aids in the exploration of diverse medicinal applications, making it an essential reagent for researchers in drug discovery and development. -
Drug Impurity
Ondansetron impurity 6 is a known impurity associated with the antinausea medication Ondansetron. This compound is essential for assessing the purity and quality of pharmaceutical formulations containing Ondansetron. It serves a critical role in research focused on drug development, formulation stability, and regulatory compliance by providing insights into the compound's synthesis and degradation pathways. -
Drug Intermediate
2-Methyl-2-propanyl(1S,8R)-4-nitro-11-azatricyclo[6.2.1.02,7]undeca-2,4,6-triene-11-carboxylate serves as a key drug intermediate in the synthesis of diverse biologically active compounds. This compound is important for creating novel agents with potential therapeutic applications, facilitating research in medicinal chemistry and pharmacology. Its structural attributes enable the development of derivatives that can target various biological pathways. -
Drug Impurity
Methyl 2-formyl-5-methoxybenzoate is identified as a drug impurity. This compound may participate in various analytical studies aimed at assessing the purity of pharmaceutical formulations. It is useful for researchers investigating the stability and degradation pathways of benzoate derivatives within the context of drug development. -
Drug Impurity
Methyl 5-formylsalicylate is a recognized drug impurity associated with various pharmaceutical compounds. This compound can serve as an important analytical marker for quality control and stability testing throughout drug development processes. Its examination can provide insights into the metabolic pathways and degradation products of certain drug formulations, aiding in the evaluation of safety and efficacy. -
Drug Impurity
Nintedanib impurity 9 is a specific impurity associated with the drug Nintedanib, which serves as a multiple receptor kinase inhibitor targeting VEGFR, PDGFR, and FGFR. This compound is utilized in research to assess the purity and quality of Nintedanib formulations. Its identification is crucial for compliance with regulatory standards in drug development and quality control processes. -
Drug Intermediate
5,6,7,8-Tetrahydro-2-naphthoic acid is a synthetic intermediate utilized in pharmaceutical synthesis. It serves as a key building block in the development of various therapeutic compounds, facilitating the design of biologically active molecules. This compound is particularly valuable in drug discovery and medicinal chemistry applications. -
Drug Impurity
Glycopyrronium impurity 4 is a chemical impurity associated with the synthesis of Glycopyrronium, a muscarinic receptor antagonist. This impurity is relevant for quality control and regulatory compliance during the development and manufacture of pharmaceutical formulations. It can be utilized in analytical studies to assess the purity and stability of Glycopyrronium formulations. -
Drug Intermediate
Bis(acetoxymethyl) 2,2'-((tert-butoxycarbonyl)azanediyl)diacetate serves as a crucial drug intermediate in the synthesis of diverse active pharmaceutical ingredients. This compound facilitates the incorporation of functional groups in medicinal chemistry applications, aiding in the development of novel therapeutic agents. Its versatility in synthetic pathways contributes significantly to pharmaceutical research and development initiatives. -
Drug Intermediate
rel-Ethyl (2R,3S)-2,3-dimethylcyclopropanecarboxylate serves as a valuable drug intermediate in the synthesis of diverse bioactive compounds. This compound is utilized in medicinal chemistry for the preparation of pharmaceuticals, allowing for the development of new therapeutic agents. Its structural characteristics facilitate various chemical reactions, making it an essential reagent in organic synthesis. -
Drug Impurity
Cinakase impurity 11 is a byproduct associated with the synthesis of Cinakase, a medication used for the treatment of certain hematological malignancies. This impurity is essential for analytical validation and quality control in pharmaceutical research. Its characterization aids in ensuring the safety and efficacy of the final therapeutic product, facilitating compliance with regulatory standards in drug development. -
Drug Impurity
Sitagliptin impurity 5 is a structural variant of Sitagliptin, primarily characterized as a drug impurity. It is utilized in pharmaceutical research and development to understand the profiles and effects of Sitagliptin formulations. This impurity plays a crucial role in chromatographic analysis and quality control assessments of Sitagliptin products, ensuring the integrity and safety of therapeutic compounds. -
Drug Impurity
Prednisolone Impurity 9 is a chemical impurity associated with the corticosteroid prednisolone. Characterizing this impurity is essential for ensuring the quality and safety of pharmaceutical formulations. This reagent is utilized in analytical and quality control studies to identify and quantify impurities, contributing to the overall understanding of drug stability and efficacy. -
Drug Impurity
Furosemide Impurity 7 is a chemical impurity associated with the pharmaceutical compound Furosemide. As a drug impurity, it is relevant for studies focusing on pharmaceutical quality control and toxicological assessments. Research applications include the evaluation of drug purity and stability, as well as understanding the implications of impurities in drug formulations. -
Drug Impurity
Ticagrelor impurity 20 is a chemical impurity associated with the antiplatelet agent Ticagrelor. This compound serves as an important reference standard in the evaluation of Ticagrelor quality and purity. It is utilized in pharmaceutical research and development to ensure the integrity of formulations containing Ticagrelor and to study the effects of impurities on drug efficacy and safety. -
Drug Intermediate
1,7-Diazaspiro[4.5]decan-6-one hydrochloride serves as a crucial drug intermediate in the synthesis of diverse bioactive compounds. Its unique spirocyclic structure facilitates the development of pharmacologically relevant molecules, enhancing research in medicinal chemistry and drug discovery. This compound is utilized in the production of a variety of therapeutic agents, contributing to advancements in pharmaceutical applications. -
Drug Impurity
Peracetyl Empagliflozin is a known drug impurity related to the SGLT2 inhibitor Empagliflozin. This compound may be utilized in the study of pharmaceutical formulations and stability testing, helping to assess the quality and safety of drug products. Its characterization can provide valuable insights into synthesis pathways and potential degradation mechanisms, supporting research in drug development and regulatory compliance. -
Drug Impurity
Avibactam impurity 1 is a chemical impurity associated with Avibactam, a β-lactamase inhibitor. This compound is critical for quality control and characterization in pharmaceutical research and development. Its analysis is essential for ensuring the purity of Avibactam in clinical formulations and contributes to investigations on drug stability and efficacy. -
Drug Impurity
Dapagliflozin impurity 57 is a chemical impurity associated with Dapagliflozin, an SGLT2 inhibitor used in the treatment of type 2 diabetes. This compound serves as a key reference standard for analytical characterization and quality control in pharmaceutical research. Its presence is crucial for ensuring the purity and safety of therapeutic formulations containing Dapagliflozin, making it essential for regulatory compliance and stability testing. -
Drug Impurity
Ropivacaine impurity 1 hydrochloride is a known impurity related to the local anesthetic Ropivacaine. This compound serves as an important reference standard for the assessment of drug quality and purity in pharmaceutical research and development. Its characterization is crucial for regulatory compliance and ensuring the safety and efficacy of Ropivacaine formulations. -
Drug Impurity
Methotrexate impurity 6 is a known impurity associated with the chemotherapeutic agent Methotrexate. This compound is primarily used for analytical purposes in pharmacokinetic studies and quality control processes. It serves as a reference standard for identifying and quantifying impurities in pharmaceutical formulations containing Methotrexate. -
Drug Intermediate
2-Amino-5-bromobenzophenone is a key intermediate in pharmaceutical synthesis, primarily targeting drug development. This compound features a bromine substitution on the benzophenone structure, facilitating its use in the production of various biologically active compounds. It is utilized in the exploration of new therapeutic agents and in research related to medicinal chemistry. -
Drug Impurity
Ticagrelor impurity 25 is a synthetic impurity associated with the antiplatelet agent Ticagrelor, acting primarily on the P2Y12 receptor to inhibit platelet aggregation. This compound serves as a crucial reference material in the analysis and quality control of Ticagrelor formulations, ensuring the purity and efficacy of the drug. Its characterization is essential for pharmacokinetic studies and the development of regulatory guidelines in pharmaceutical research. -
Drug Impurity
Trimetazidine impurity 10 is a chemical impurity associated with the cardioprotective agent Trimetazidine. As a research reagent, it can be utilized in the analysis of Trimetazidine's purity and stability, helping to ensure compliance with pharmacological standards. This impurity is significant for studies involving drug formulation and quality control in pharmaceutical research. -
Drug Intermediate
3-Formyl-1-(phenylsulphonyl)-1H-indole serves as a versatile drug intermediate in the synthesis of various biologically active compounds. Its structure facilitates the formulation of indole derivatives, which are significant in medicinal chemistry. This compound is particularly useful in research applications focused on the development of pharmaceuticals with targeted therapeutic effects. -
Drug Impurity
Sorafenib impurity 6 is a known impurity of the multikinase inhibitor Sorafenib, targeting various receptor tyrosine kinases involved in tumor angiogenesis and cell proliferation. This compound serves as a useful reference standard in analytical chemistry and pharmacokinetic studies to assess the purity of Sorafenib formulations. Its characterization aids in ensuring the quality and efficacy of pharmaceutical products containing Sorafenib.
