Catalog No.
Product Name
Application
Product Information
Citations
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Drug Impurity
Voriconazole impurity 1 is a recognized impurity of the antifungal agent Voriconazole, which targets fungal cytochromes P450 to inhibit ergosterol synthesis. This compound is utilized in the evaluation of pharmaceutical purity and stability studies, as well as in toxicological assessments. Its presence can impact the safety profile and efficacy of Voriconazole in clinical applications. -
Drug Impurity
Nintedanib Impurity 10 is a chemical impurity associated with Nintedanib, a targeted therapy for various fibrotic diseases. This compound serves as a reference standard for the analytical assessment of Nintedanib formulations, ensuring the quality and consistency of pharmaceutical preparations. Its presence is critical for quality control and regulatory compliance in drug development processes. -
Drug Impurity
Mivacurium chloride impurity 6 is a known impurity associated with the neuromuscular blocker Mivacurium chloride. It serves as a critical reference compound for quality assurance and method validation in pharmaceutical development. This impurity can be utilized in analytical studies to assess the purity of Mivacurium chloride formulations and to understand potential effects on safety and efficacy in drug manufacturing processes. -
Drug Intermediate Control
2-Pyrimidinepropanoic acid is a synthetic intermediate primarily utilized in pharmaceutical synthesis. This compound serves as a key building block in the development of various bioactive molecules and drug candidates, facilitating research in medicinal chemistry. Its role in the modification of bioactive compounds makes it valuable for applications in drug discovery and development. -
MRX-I Prodrug Intermediate
Contezolid phosphoramidic acid is a key intermediate in the synthesis of MRX-I, an antibacterial oxazolidinone agent. This compound plays a critical role in the development of proagents designed to combat bacterial infections. Its relevance in medicinal chemistry makes it an essential reagent for research applications focused on antibiotic efficacy and development. -
Drug Intermediate
5-Ethoxy-4-methyloxazole is a chemical intermediate primarily utilized in the synthesis of pharmaceutical compounds. This heterocyclic compound contributes to the development of various drug candidates by serving as a building block in organic synthesis. Its structural characteristics support research in medicinal chemistry and the design of novel therapeutics. -
Drug Intermediate
tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate serves as an important intermediate in the synthesis of potent DP2 receptor antagonists derived from a novel spiro-indolinone framework. This compound is significant for its role in drug discovery, particularly in the development of therapeutics aimed at modulating immune responses and inflammation pathways. Researchers utilize this intermediate to facilitate the creation of compounds with potential clinical applications in treating allergic and inflammatory diseases. -
Drug Intermediate
Stemmadenine is a strychnos-type monoterpenoid indole alkaloid that functions as a crucial biosynthetic precursor in the formation of monoterpenoid indole alkaloid structures. Its primary mechanism involves contributing to the synthesis of complex alkaloids, making it valuable in drug development and research into natural product synthesis. Stemmadenine is utilized extensively in studies focused on the biosynthetic pathways of alkaloids and their potential therapeutic applications. -
Drug Intermediate
(2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative primarily utilized as a drug intermediate in the synthesis of antibody-drug conjugate (ADC) linkers. Its structural features contribute to the development of more effective targeted therapies in oncology research. This compound serves as a valuable building block in the formulation of bioconjugates, enhancing the specificity and efficacy of therapeutic agents. -
Drug Intermediate
2-Phenylacrylonitrile is a versatile pharmaceutical intermediate that serves as a precursor in the synthesis of various compounds. Its derivatives are utilized in cancer research, particularly in the development of cancer therapeutics and mechanisms of action studies. This compound provides essential building blocks for the exploration of anticancer agents and their biological activity. -
Drug Intermediate
Fmoc-PNA-maleimide-OH is a Fmoc-protected peptide nucleic acid monomer that incorporates a maleimide moiety, enabling selective thiol-reactive conjugation. This compound facilitates the construction of peptide nucleic acid (PNA) conjugates, which are valuable in molecular assembly and bioconjugation applications. Its unique functionalization allows for enhanced versatility in the design of nucleic acid-based tools for research and therapeutic development. -
Phosphoramidite Compound
3'-NH-Tr-2',3'-dT-5'-CE-Phosphoramidite is a phosphoramidite compound utilized in the synthesis of oligonucleotides and nucleic acid analogs. It plays a crucial role in the development of antiviral and anticancer research applications. This reagent facilitates the incorporation of modified nucleotides, enabling the exploration of therapeutic strategies in nucleic acid-based interventions. -
Drug Intermediate
Erlotinib lactam impurity is a chemical precursor of the tyrosine kinase inhibitor erlotinib. This compound serves as an important intermediate in the synthesis of anti-cancer therapeutics, particularly in the study of targeted therapies for non-small cell lung cancer. Its role in drug development makes it a valuable reagent for research applications focused on kinase inhibition and related signaling pathways. -
Drug Intermediate
3-(Trimethylsilyl)-1-propanesulfonic acid sodium functions as a drug intermediate, facilitating various chemical reactions. This compound serves as a versatile reagent in the synthesis of peptides, proteins, and nucleic acids. Its efficacy in stabilizing reactive intermediates makes it a valuable tool for researchers in biochemical and pharmaceutical applications. -
Drug Intermediate
5-Br-4-Cl-Pyrrolo-pyroxypyridine serves as a synthetic intermediate for molecular glues. It is particularly relevant in the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation. This compound is essential for research applications focused on proteostasis and the modulation of protein interactions. -
Drug Intermediate
4-Hydroxy-3,3-dimethylcyclohexanone serves as a crucial intermediate in the synthesis of human acetylcholinesterase (hAChE) inhibitors. Its role in the development of hAChE inhibitors makes it significant for research in neuropharmacology and disease models related to cholinergic dysfunction. This compound's unique structural properties facilitate the exploration of therapeutic agents targeting cognitive disorders. -
Drug Impurity
Dexamethasone impurity 2 is a chemical impurity associated with Dexamethasone. It serves as an important reference standard for purity analysis and quality control in pharmaceutical research. This compound aids in the assessment and characterization of Dexamethasone formulations, facilitating compliance with regulatory standards. -
Degradation Impurity in Docetaxel
7-epi-10-Oxo-10-deacetyl baccatin III is a degradation impurity found in Docetaxel. This compound is important for research involving the stability and degradation pathways of taxane-based chemotherapeutics. It serves as a vital reference standard for evaluating the purity and efficacy of Docetaxel formulations, thus aiding in the development of stable therapeutic agents. -
Drug Intermediate
H-Aeg(Fmoc)-OBzl hydrochloride is an Fmoc-protected aminoethylglycine derivative with a benzyl ester moiety. It serves as a versatile drug intermediate, facilitating the synthesis of peptide nucleic acids and protected oligomers. This compound is valuable in various research applications, including peptide synthesis and molecular biology studies. -
Drug Intermediate
LY280748 is a potent imidazolate receptor ligand, functioning primarily as a drug intermediate. This compound exhibits significant biological activity, making it a valuable tool in pharmacological research and development. Its application spans various studies focused on receptor-mediated signaling pathways and the synthesis of novel therapeutic agents. -
Drug Impurity
Cyclosporin impurity 2, also known as Acetoxy cyclosporin A acetate, is a known impurity of cyclosporin. This compound may arise during the synthesis or formulation of cyclosporin and can be important for analytical and quality control purposes in pharmaceutical research. It serves as a reference standard for the evaluation of cyclosporin purity and plays a critical role in the assessment of drug safety and efficacy. -
Drug Intermediate
GA44 is a C20-gibberellin that serves as an intermediate in the early 13-hydroxylation pathway of gibberellin biosynthesis. This compound plays a critical role in the synthesis of biologically active gibberellins, which are important regulators of plant growth and development. GA44 is utilized in research applications focusing on plant hormone signaling and metabolism studies. -
Drug Intermediate
H-Aeg(Fmoc)-OH hydrochloride is an Fmoc-protected aminoethylglycine monomer that features a free carboxyl group. This reagent serves as a versatile building block for peptide nucleic acid synthesis, facilitating the construction of PNA oligomers. Its chemical structure supports the incorporation of aminoethylglycine into various bioconjugates, making it valuable in nucleic acid research and related fields. -
Drug Intermediate
N,N'-bis-Cbz-β-Alethine is an active ester that serves as a crucial intermediate in the synthesis of β-alethine. β-Alethine has been shown to induce cell differentiation and exhibits potential anti-tumor properties. The conversion of N,N'-bis-Cbz-β-Alethine to β-alethine is achieved through the removal of the carbobenzoxy (CBZ) groups using hydrogen bromide in glacial acetic acid. This compound is valuable for research focused on cell differentiation mechanisms and anti-cancer drug development. -
Drug Intermediate
Azidoethyl-oxime-Glucose-GalNAc serves as a versatile drug intermediate, primarily aimed at synthesizing disaccharide linkers. This compound plays a crucial role in the development of glycan site-directed antibody-drug conjugates (ADCs), facilitating targeted delivery in therapeutic applications. Its unique chemical structure allows for efficient modification and incorporation into complex carbohydrates, making it essential for advancing glycoscience research and drug development. -
Drug Intermediate
K-13 is a cyclic peptide compound that serves as a valuable drug intermediate through its role in organic synthesis. Its production involves a highly efficient synthetic route utilizing intermolecular and intramolecular Negishi cross-coupling reactions. This streamlined synthesis approach makes K-13 a significant reagent for research applications in drug development and peptide chemistry. -
Drug Intermediate
Methoxycarbonyl isocyanate serves as a versatile drug intermediate primarily utilized in organic synthesis. Its reactive isocyanate group allows for the formation of various carbamates and ureas, making it valuable in the development of pharmaceutical compounds. This reagent is essential for studying and optimizing synthetic pathways in drug discovery and development. -
Drug Intermediate
Guaietolin is an organic synthesis intermediate primarily used in the development of sulfonamide esters that exhibit carbonic anhydrase inhibitory activity. It serves as a significant marker of hypertension, as its levels are notably reduced in plasma metabolites of affected individuals. Guaietolin is applicable in research focused on glaucoma and hypertension, providing a valuable tool for investigating these cardiovascular and ocular conditions. -
Drug Impurity
(2,3-Dimethoxyphenyl)methanol is identified as a drug impurity often encountered during the synthesis of various pharmaceutical compounds. Its structural features may influence the physicochemical properties of the primary drug substance. This compound is relevant for analytical studies focused on purity assessment and stability testing within pharmaceutical research and development. -
Drug Intermediate
Bimatoprost isopropyl ester acts as a drug intermediate with a specific focus on the prostaglandin F2α analogs. It is characterized by a double bond at the 13-14 position and an inverted hydroxyl group at C-15. Notably, this compound has demonstrated significant biological activity, exhibiting an IC50 of 30 nM in FP receptor binding assays, indicating its potential role as an impurity in latanoprost formulations. Additionally, in vivo studies revealed that a dose of 3 μg can lead to a 1.9 mmHg decrease in intraocular pressure in normotensive cynomolgus monkeys, making it a valuable reagent for research involving ocular therapies. -
Drug Intermediate
Fmoc-Aeg-OtBu is a versatile intermediate used in solid-phase peptide synthesis. It acts as a building block for the introduction of pseudoproline motifs and backbone modifications, enhancing the stability and folding properties of peptides. This compound is essential for researchers developing peptide therapeutics and studying protein structure and function. -
Drug Intermediate
1-epi-Regadenoson ethyl ester is a key intermediate in the synthesis of the α-isomer impurity of Regadenoson, a highly selective agonist for the adenosine A2A receptor. This compound is essential for research involving adenosine receptor biology and contributes to the understanding of cardiovascular function and cellular signaling pathways. Its application extends to the development and analysis of therapeutic agents targeting adenosine receptors. -
Drug Impurity
Ranolazine impurity 10 is a chemical impurity associated with the cardiovascular drug Ranolazine, which primarily targets sodium channels. This impurity is significant for analytical and quality control purposes in pharmaceutical research and development, aiding in the assessment of the drug's purity and safety profile. Its identification and quantification are critical for compliance with regulatory standards in the drug manufacturing process. -
Drug Intermediate
LBA-NHS is a derivative of lactobionic acid (LBA) designed as a drug intermediate. It functions by enabling the modification of lipids and acts as a coating for biological materials, enhancing the efficient and specific binding of LBA to carrier molecules. This compound is valuable in research applications involving drug delivery systems and biomaterials engineering. -
Drug Intermediate
5β-Dihydrocortisone acetate serves as a crucial intermediate in the synthesis of tetrahydrocortisone 3-glucuronide. This compound plays a significant role in biochemical research and pharmaceutical development, particularly in the study of corticosteroid metabolism and glucuronidation processes. Its use can facilitate investigations into the pharmacokinetics of glucocorticoids and their conjugates, contributing to a better understanding of steroid biochemistry. -
Drug Intermediate
1-Amino-3-(phosphonooxy)-2-propanone acts as a crucial drug intermediate in the synthesis of vitamin B6. This compound facilitates biochemical reactions essential for the production of vitamin B6 derivatives, contributing to studies in nutrition and metabolism. Its application in synthetic pathways enhances research related to vitamin synthesis and potential therapeutic developments. -
Drug Impurity
Fingolimod impurity 3 is identified as a chemical impurity associated with Fingolimod, a sphingosine 1-phosphate receptor modulator. This compound serves as an important reference for assessing the purity and quality of Fingolimod formulations in pharmaceutical research. Its presence may influence the pharmacological profile and efficacy of the parent drug, making it a valuable component in analytical studies and quality control processes. -
Drug Intermediate
AldoView precursor-1 is a crucial intermediate in the synthesis of the radioactive PET tracer [18F] AldoView. This compound serves as a selective tracer for imaging aldosterone synthase activity, making it valuable in the study of primary hyperaldosteronism. Its application facilitates non-invasive imaging and further research into aldosterone-related disorders. -
Drug Intermediate
Citreomontanin, an α-Pyrone polyketide, serves as a key drug intermediate in the synthesis of Citreoviripyrone A. Isolated from the mycelium of endophytic Penicillium species in Catharanthus roseus, Citreomontanin plays a critical role in facilitating research on compounds with biological activity. Notably, Citreoviripyrone A exhibits moderate inhibitory effects on the proliferation of HCT116 colorectal cancer cells, highlighting its potential utility in cancer research and drug development. -
Drug Intermediate
Fmoc-Aeg-OMe hydrochloride is a methyl ester derivative of Fmoc-protected aminoethylglycine, primarily used as a drug intermediate in chemical synthesis. This compound plays a crucial role in the synthesis of polyamide nucleic acids, facilitating research in nucleic acid chemistry and related fields. Its unique structure and properties make it valuable for developing novel therapeutic agents and exploring biomolecular interactions. -
Drug Intermediate
Valone is a critical intermediate in the synthesis of diorganotin(IV) complexes. Its unique chemical properties facilitate the creation of organotin compounds, which are essential in various applications, including agricultural and pharmaceutical research. This reagent serves as a fundamental building block for the development of advanced materials and bioactive substances in chemical research. -
Drug Intermediate
5-Bromo-1,2-difluoro-3-methoxybenzene serves as a crucial drug intermediate in synthetic chemistry. It functions as a precursor for the development of glucocorticoid receptor (GR) ligands, enabling the exploration of GR-targeted therapies. This compound is applicable in pharmaceutical research for the synthesis of novel therapeutic agents. -
Drug Intermediate
Geranylamine is an acyclic monoterpene amine that functions as a drug intermediate in the synthesis of various TRP channel modulators and antibacterial agents. Its structural properties make it a valuable precursor in medicinal chemistry, facilitating the development of compounds aimed at modulating ion channel activity and addressing bacterial resistance. This compound plays a crucial role in advancing research in pharmacology and therapeutic applications. -
Drug Intermediate
DFO-BCN is a chemical intermediate utilized in the synthesis of the PET/CT imaging agent DFO-CPC634 via click chemistry. This compound serves as a valuable tool in radiopharmaceutical development, enabling effective labeling and visualization in molecular imaging studies. Its role as a precursor enhances the efficiency of tracer synthesis, supporting research in diagnostic imaging applications. -
Drug Intermediate
((4-(tert-Butyl)phenyl)sulfonyl)methionine serves as a versatile drug intermediate in chemical synthesis. This compound is primarily utilized for the construction of peptides, facilitating the creation of diverse biological molecules. Its sulfonyl group enhances the stability and efficacy of peptide linkages, making it a valuable reagent in medicinal chemistry and drug development research. -
Drug Impurity
Rivaroxaban impurity 69 is a chemical impurity associated with the anticoagulant drug Rivaroxaban. It is commonly utilized in analytical research to assess the purity and quality of Rivaroxaban formulations. Understanding the presence of this impurity is critical for ensuring the safety and efficacy of therapeutic applications involving Rivaroxaban. -
Drug Intermediate
2,4,6-Tribromo-3-methylphenol is a brominated phenolic compound widely utilized as a drug intermediate. It exhibits significant biological activity, serving as a precursor in the synthesis of various pharmaceuticals. Researchers employ this compound in studies related to organic synthesis and medicinal chemistry, facilitating the development of novel therapeutic agents. -
Drug Intermediate
(S)-Oxybutynin is a key pharmaceutical intermediate primarily involved in the synthesis of antifungal agents. This compound serves as an important building block in drug development, facilitating the creation of therapeutically relevant molecules. Its role in the synthesis pathway underscores its significance in both medicinal chemistry and pharmaceutical applications. -
Drug Intermediate
Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate primarily employed in the development of molecular glues. This compound serves as a crucial building block for the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation research and applications in drug discovery. Its structural properties make it valuable in the design of innovative therapeutic agents. -
Drug Intermediate
Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a key intermediate for drug synthesis, primarily targeting biphenyl-based derivatives. This compound serves as a versatile building block in the development of various pharmaceuticals, facilitating the preparation of more complex molecules in medicinal chemistry. Its structural features make it valuable for applications in drug discovery and development.
