Catalog No.
Product Name
Application
Product Information
Citations
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Drug Impurity
Glimepiride impurity 1 is identified as a chemical impurity associated with the antidiabetic agent Glimepiride. It is critical for quality control and characterization in pharmaceutical research, particularly in the development and validation of analytical methods for Glimepiride formulations. This impurity aids in the assessment of drug purity and stability, ensuring compliance with regulatory standards in drug manufacturing. -
Drug Impurity
5-Nitrobenzofuran is identified as a drug impurity with potential relevance in pharmaceutical research. It may be generated during the synthesis of certain drug compounds and can influence the efficacy and safety profiles of these pharmaceuticals. Understanding its properties and behavior is crucial for the optimization of drug formulation and quality control in the development of therapeutic agents. -
Drug Impurity
Apixaban impurity 10 is a chemical byproduct associated with the synthesis of Apixaban, an oral anticoagulant that selectively inhibits factor Xa. This impurity is essential for quality control and analytical studies to ensure the purity and efficacy of Apixaban formulations. Research applications include utilization in method development, validation processes, and stability studies within pharmaceutical research. -
Drug Impurity
Buspirone impurity 9 is identified as an impurity of the anxiolytic compound Buspirone. This chemical can be utilized in research focused on drug purity and formulation, serving as a reference standard for analytical testing. Its characterization is essential for understanding the pharmacological profiles and safety assessments of Buspirone-related products in pharmaceutical development. -
Drug Impurity
Ticagrelor impurity 5 is a chemical impurity associated with the antiplatelet medication Ticagrelor, primarily targeting the P2Y12 receptor. This reagent is crucial for the analysis of drug purity and quality control in pharmaceutical research. Its identification and quantification can aid in the assessment of synthetic processes and help ensure the safety and efficacy of Ticagrelor formulations. -
Drug Intermediate
Fmoc-Asp(OMpe)-Cbz is a key drug intermediate employed in the synthesis of Fmoc-Asp(OMpe)-OH. This compound allows for the efficient assembly of peptide sequences, particularly those requiring protected aspartic acid derivatives. Its applications include peptide synthesis in pharmaceutical research and development, aiding in the exploration of peptide-based therapeutics. -
Drug Impurity
Afatinib impurity 5 is a chemical impurity associated with the tyrosine kinase inhibitor Afatinib, which primarily targets EGFR and HER2 pathways. This impurity can be utilized in quality control and characterization studies for drug development, ensuring the purity and efficacy of pharmaceutical formulations. Detailed analysis of impurity profiles, such as Afatinib impurity 5, is crucial for compliance with regulatory standards in drug manufacturing. -
Drug Intermediate
7-Bromo-5-chloro-2,3-dihydropyrano[4,3,2-de]quinoline serves as a crucial drug intermediate in organic synthesis. Its structure provides a framework for the development of a variety of biologically active compounds. This reagent is particularly useful in the pharmaceutical industry for the creation of novel therapeutics and in medicinal chemistry research. -
Drug Intermediate
3,3'-Bipyridine is a versatile ligand utilized in coordination chemistry, primarily serving as a drug intermediate. It acts as a chelating agent, effectively enhancing the reactivity of metal complexes. This compound is particularly valuable in catalysis, often employed in conjunction with BINOL to promote various catalytic reactions in synthetic organic chemistry. -
Drug Impurity
Afatinib impurity 1 (also known as Afatinib Impurity CSEJXA) is a chemical impurity associated with the drug Afatinib, which functions as an irreversible inhibitor of the epidermal growth factor receptor (EGFR). This impurity is essential for the characterization and quality control of Afatinib in pharmaceutical development and can be utilized in research focusing on EGFR-targeted therapies. Understanding the profile of Afatinib impurity 1 helps ensure the integrity and safety of EGFR-inhibiting compounds in various biological applications. -
Drug Intermediate
1-((Benzyloxy)carbonyl)-5-oxopiperidine-2-carboxylic acid serves as a key drug intermediate in the synthesis of diverse bioactive molecules. This compound is utilized in pharmaceutical research for the development of new therapeutic agents. Its structural framework supports various chemical modifications, facilitating the exploration of novel pharmacological properties. -
Drug Intermediate
1-(1-(2-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-methylpiperazine functions as an important drug intermediate in the synthesis of diverse active pharmaceutical compounds. Its structure promotes interactions that are critical in drug development, making it essential for researchers focusing on pharmacological studies and medicinal chemistry applications. This compound aids in the exploration of therapeutic targets and contributes to the advancement of new drug discovery projects. -
Aspartame Impurity
Cyclo(Phe-Asp) is a cyclic dipeptide that serves as an impurity associated with Aspartame. This compound is utilized in chemical research to study the structural characteristics and purity of Aspartame formulations. Its presence can affect the overall quality and efficacy of Aspartame in various applications, making it an important marker in analytical studies of artificial sweeteners and related compounds. -
Drug Impurity
Donepezil impurity 15 is a chemical impurity associated with Donepezil, a reversible inhibitor of acetylcholinesterase. This impurity can serve as a reference standard in analytical and quality control laboratories for the characterization of Donepezil formulations. Research applications include stability testing, impurity profile assessments, and compliance with regulatory requirements in drug development. -
Drug Impurity
cis-4-[Bis(phenylmethyl)amino]cyclohexanemethanol is characterized as a drug impurity. This compound may be utilized in studies examining the safety and efficacy of pharmaceuticals by promoting a better understanding of impurity profiles. Its relevance spans analytical methods in drug development and quality control assessments, providing insights into the pharmacological implications of related compounds. -
Drug Intermediate
(1R,3S)-3-Aminocyclopentane carboxylic acid is a chiral drug intermediate with potential applications in pharmaceutical synthesis. This compound serves as a building block for the development of various biologically active molecules. Its unique structure and functionalities make it valuable in the design of novel therapeutics and in the exploration of cyclopentane derivatives in medicinal chemistry. -
Drug Intermediate
2-(Methoxy(4-phenoxyphenyl)methylene)malononitrile serves as a vital drug intermediate in the synthesis of diverse active pharmaceutical ingredients. This compound facilitates the development of novel therapeutics by providing a versatile scaffold for further chemical modifications. Its role is crucial in advancing research in medicinal chemistry and drug discovery. -
Drug Impurity
Ramelteon impurity 10 is a known impurity of the sleep-aid compound Ramelteon, which primarily acts as a melatonin receptor agonist. This reagent is crucial for analyzing the purity of Ramelteon formulations in pharmaceutical research and quality control. Its presence can influence pharmacological outcomes and stability studies, making it essential for thorough characterizations in drug development. -
Drug Impurity
Bedaquinoline impurity 1 is a chemical impurity associated with Bedaquinoline, a compound used in the treatment of tuberculosis. This impurity can affect the efficacy and safety profile of Bedaquinoline-containing formulations. It is useful for analytical research, particularly in the development and quality control of anti-tuberculosis medications. -
Goserelin Impurity
Goserelin EP Impurity E is an impurity of Goserelin that serves as a valuable reference standard in analytical chemistry. It is used primarily for the characterization and quality control of Goserelin formulations in pharmaceutical research. This compound aids in assessing the purity and stability of Goserelin, ensuring that drug preparations meet regulatory standards in therapeutic applications. -
Drug Intermediate
4-Chloronaphthalimide is a derivative of naphthalimide that serves as a valuable drug intermediate in pharmaceutical synthesis. This compound plays a crucial role in the development of diverse bioactive molecules due to its reactivity and ability to participate in various chemical transformations. Its applications extend to medicinal chemistry and the exploration of novel therapeutic agents. -
Pheromone
5-Methyldecane is a volatile hydrocarbon identified as a pheromone, primarily sourced from the plant Cordia Africana. This compound has been observed to be released by the marine annelid Platynereis dumerilii, contributing to its role in chemical communication. Its biological activity makes it valuable for research in behavioral ecology and pheromone signaling mechanisms. -
Exenatide Impurity
(D-Asp28)-Exenatide is an impurity of Exenatide, which functions as a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist. This compound plays a significant role in the regulation of glucose homeostasis and appetite control, making it relevant for research in diabetes and obesity. The characterization of this impurity is essential for understanding the pharmacological properties and ensuring the quality of Exenatide in therapeutic applications. -
Derivative of Prostaglandin H1
9,11-Methane-epoxy prostaglandin F1α is a derivative of prostaglandin H1 that targets various smooth muscle tissues. It effectively induces platelet aggregation in isolated rabbit platelets (EC50=0.88 µM) and promotes contraction in rabbit aortic strips (EC50=0.11 µM). Additionally, 9,11-methane-epoxy prostaglandin F1α demonstrates significant contractile activity in isolated guinea pig tracheas (EC50=3.4 µM). This compound is valuable for research applications related to cardiovascular and respiratory pharmacology. -
Drug Derivative
N-(4-Hydroxyphenylacetyl)spermine is a drug derivative that acts as a potent cellular growth regulator. It exhibits significant biological activity by modulating polyamine metabolism and influencing cell signaling pathways. This compound is commonly utilized in cancer research to study its effects on cell proliferation and apoptosis, making it a valuable tool for investigating therapeutic strategies in oncology. -
Drug Derivative
L-670,548 is a selective inhibitor of the neurokinin-1 (NK1) receptor, functioning as a drug derivative in research applications. It displays significant anti-nociceptive properties, making it relevant for studies in pain modulation and neurobiology. Researchers utilize L-670,548 to explore the mechanisms of pain signaling and potential therapeutic targets for pain management. -
Drug Derivative
AHN 086 is a small molecule drug derivative that acts as a selective inhibitor of histone deacetylases (HDACs). It exhibits significant anti-proliferative effects in various cancer cell lines by disrupting histone and non-histone protein deacetylation, thus influencing gene expression. This compound is primarily utilized in cancer research and studies investigating epigenetic regulation mechanisms. -
Drug Derivative
SRX251 is a drug derivative that acts primarily as a serotonin receptor antagonist. It demonstrates significant biological activity in modulating serotonergic signaling pathways, which may be relevant in the study of neuropsychiatric disorders. This compound is utilized in research focused on understanding the therapeutic potential of serotonin modulation in various clinical applications. -
Drug Derivative
MDPT (tBuONE) is a derivative of 3',4'-Methylenedioxy-N-tert-butylcathinone, primarily targeting monoamine transporters. This compound exhibits stimulant properties, making it relevant for research focusing on neuropharmacology and the mechanisms of drug addiction. Its structural similarity to known psychoactive substances enables investigations into their pharmacodynamic profiles and potential therapeutic applications. -
Drug Derivative
LB30870 is a drug derivative that demonstrates active pharmacological properties. This compound is utilized in research applications aimed at investigating its potential biological activities and therapeutic effects. Its specific mechanisms and pathways are of interest in the development of novel treatments. -
Drug Derivative
2-Methyl-1-naphthol acts as a crucial precursor in the biosynthesis of Vitamin K3. This compound is relevant for studying Vitamin K deficiency, aiding in the exploration of its implications in various biological processes and potential therapeutic applications. Its derivatives are utilized in research focused on enhancing understanding of Vitamin K's role in health and disease. -
Drug Derivative
NC-1300-B is a potent drug derivative that exhibits significant biological activity through its interaction with specific molecular targets. This compound is primarily used in research focused on drug development and mechanism studies, enabling scientists to explore its therapeutic potential in various disease models. Its specific structural properties make it a valuable tool for investigating novel treatment pathways in pharmacology. -
Drug Derivative
Dactylocycline D is a drug derivative that functions primarily as an antibiotic by inhibiting bacterial protein synthesis. It exhibits potent antibacterial activity against a variety of gram-positive and gram-negative bacteria, making it valuable in pharmacological research focused on antimicrobial mechanisms. This compound is applicable in studies that aim to explore its efficacy, resistance mechanisms, and potential therapeutic uses in infectious diseases. -
Impurity
5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an impurity associated with the synthesis of Capecitabine. This compound may be used in analytical studies to ensure the purity and quality of Capecitabine preparations. Its identification and characterization contribute to the understanding of the synthesis process and its optimization in pharmaceutical development. -
Drug Derivative
α-Pyrrolidinocyclohexanophenone hydrochloride is a psychostimulant compound primarily targeting the dopamine transporter. It demonstrates notable biological activity as a potent reuptake inhibitor, leading to increased dopaminergic signaling. This compound is primarily utilized in neurological research, particularly in studies exploring the pharmacological effects on mood, cognition, and addiction mechanisms. -
Drug Derivative
4-Hydroxyisophorone is a derivative of abscisic acid that exhibits a weak inhibitory effect on plant growth. This compound is utilized in research to explore plant hormone interactions and their physiological effects. It serves as a valuable tool for investigating the mechanisms of plant development and response to environmental stressors. -
Drug Derivative
(R)-ADR 882, a derivative of the drug class, exhibits potent biological activity by interacting with specific cellular targets. This compound is primarily utilized in research applications focused on pharmacological studies and the development of therapeutic agents. Its efficacy in modulating biological pathways makes it a valuable tool for investigating disease mechanisms and evaluating potential drug candidates. -
Biochemical Assay Reagent
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid primarily involved in stabilizing the lipid bilayer of cell membranes. Its role as a key component enhances membrane integrity and fluidity, making it a valuable reagent for various biochemical assays. This compound is essential for studying membrane dynamics, cellular signaling, and lipid-protein interactions in research applications. -
Biochemical Reagent
γ-Glutamyltransferase (GGT) from porcine kidney is an enzyme that plays a crucial role in the metabolism of glutathione. It achieves this by cleaving extracellular glutathione, thereby enhancing the availability of amino acids and maintaining cytoplasmic glutathione levels, which are vital for cellular defense against oxidative stress. GGT from porcine kidney is primarily utilized in biochemical research, particularly in studies related to pancreatic cancer. -
Biochemical Assay Reagent
Malondialdehyde tetrabutylammonium serves as a biochemical assay reagent and is recognized as a significant biomarker for oxidative stress. This compound can effectively indicate lipid peroxidation, providing crucial insights into cell damage and overall oxidative status. Its applications extend across food and cosmetic research, where it is utilized to monitor product stability and safety. Additionally, Malondialdehyde tetrabutylammonium may serve as a potential biomarker for a variety of diseases, aiding in the exploration of pathophysiological mechanisms. -
Biochemical Assay Reagent
3-Hydroxyoctanoic acid acts as an agonist for the orphan receptor GPR109B, promoting an increase in intracellular calcium levels in human neutrophils expressing this receptor. This hydroxylated fatty acid, which occurs in the lipopolysaccharides of Pseudomonas aeruginosa and in poly(3-hydroxyalkanoate) produced by Pseudomonas oleophores, plays a role in metabolic studies. Research indicates that 3-hydroxyoctanoic acid interferes with lipolysis in human adipocytes and demonstrates significant changes in plasma levels under various dietary conditions, making it a valuable reagent for biochemical assays focused on metabolic regulation and related disorders. -
Biochemical Reagent
(S)-2-Hydroxybutanoic acid is the S-enantiomer of 2-Hydroxybutanoic acid, a biochemical reagent with significant roles in metabolic studies. This compound serves as a biomarker for insulin resistance, providing insights into metabolic disorders and protein metabolism. Its application in research is crucial for understanding the pathways associated with insulin signaling and metabolic health. -
Biochemical Assay Reagent
Amylose is a polysaccharide that primarily functions as a biochemical assay reagent. It interacts with proteins and free fatty acids through non-covalent forces, such as hydrophobic and electrostatic interactions, facilitating the formation of ternary complexes. This characteristic is essential in the study of starch structure and digestion, making amylose pivotal in food science and carbohydrate metabolism research. Additionally, it plays a significant role in investigations focused on controlling glycemic responses by influencing the rate of starch digestion. -
Biochemical Assay Reagents
α-Lactose hydrate, a disaccharide composed of glucose and galactose, serves as a crucial biochemical assay reagent. It exists in two isomeric forms, α and β, and plays significant roles in the food and pharmaceutical industries. Its applications include acting as a bulking or agglomerating agent, as well as a diluent for various compounds such as pigments, flavors, and enzymes, facilitating diverse biochemical analyses and formulations. -
Drug Intermediate
5-Methoxyindole is an indole derivative that serves as a crucial intermediate in drug synthesis. It is primarily utilized to produce compounds such as 5-methoxytryptophan and N-acetyl 5-methoxytryptamine. This compound demonstrates significant anti-cancer and anti-inflammatory activities, making it relevant for research in oncology and inflammation-related studies. -
Biochemical Assay Reagent
3-Penten-2-one is a biochemical assay reagent that modulates nitric oxide production by inhibiting inducible nitric oxide synthase expression. This compound exerts its effects through the induction of heme oxygenase-1 in RAW264.7 macrophages activated by lipopolysaccharides (LPS). Its applications extend to studies involving inflammatory responses and the regulation of oxidative stress. -
Biochemical Assay Reagent
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC) is a phospholipid that exhibits dual fatty acid composition, featuring palmitic acid at the sn-1 position and arachidonic acid at the sn-2 position. PAPC plays a significant role in studies involving oxidative stress, as its oxidation products are implicated in chronic inflammation and vascular diseases. This reagent is widely utilized in biochemical assays to investigate the signaling pathways associated with oxidized phospholipids. Additionally, reduced levels of PAPC have been observed in isolated human multiple myeloma cells, highlighting its relevance in cancer research. -
Biochemical Assay Reagent
Dextrin is a low molecular weight carbohydrate resulting from starch hydrolysis. As a biochemical assay reagent, it serves as an effective thickener, stabilizer, and binder in food formulations, enhancing texture and shelf-life. In addition to its applications in food production, dextrin is integral to various industrial processes, including adhesives, paper, textiles, construction, and packaging, due to its unique chemical properties. -
Biochemical Reagent
6-Hydroxyindole is a biochemical reagent that serves as a long-lasting inhibitor of the organic anion transporting polypeptide 1B1 (OATP1B1). This compound is notably elevated in the plasma of patients with renal failure, providing insights into its role in drug metabolism and transport. Its applications in research include studies on pharmacokinetics, drug interactions, and the physiological effects related to renal impairment. -
Drug Intermediate
D-Threonine is an important unnatural amino acid primarily utilized as a chiral building block in pharmaceutical synthesis. As a metabolite of Saccharomyces cerevisiae, it plays a crucial role in various biochemical pathways. D-Threonine can be enzymatically cleaved by D-threonine aldolase to yield glycine and acetaldehyde, highlighting its potential in drug development and metabolic research applications.
