Paclitaxel-2′-succinate NHS ester

Catalog No.: A54822
Paclitaxel Derivative
Paclitaxel-2'-succinate NHS ester is a reactive paclitaxel derivative that features a succinic acid linker with a highly activated NHS ester group. This compound facilitates efficient conjugation with amino or hydroxyl groups, making it suitable for coupling with peptides, proteins, antibodies, enzymes, or polymers. Its applications extend to the development of innovative nanomedicines and the exploration of targeted strategies in cancer therapy.
Grouped product items
Size Price Stock Qty
1mg
$175.00
In stock
5mg
$305.00
In stock
10mg
$505.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPaclitaxel-2'-succinate NHS ester is a reactive paclitaxel derivative that features a succinic acid linker with a highly activated NHS ester group. This compound facilitates efficient conjugation with amino or hydroxyl groups, making it suitable for coupling with peptides, proteins, antibodies, enzymes, or polymers. Its applications extend to the development of innovative nanomedicines and the exploration of targeted strategies in cancer therapy.
Product Information
Catalog NumA54822
FormulaC55H58N2O19
Molecular Weight1051.05
CAS Number245110-80-9
SMILESCC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCC(ON5C(CCC5=O)=O)=O)=O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C)C)O)OC(C8=CC=CC=C8)=O)=O
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