Pamapimod (R-1503)

Catalog No.: A13551

p38 MAPK inhibitor

Pamapimod (R-1503)

Pamapimod (R-1503) Chemical Structure

CAS NO. 449811-01-2

Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$600.00
25 mg
$1,200.00
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Biological Activity

Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
Targets
p38α MAPK p38β MAPK
0.014 μM0.48 μM
In vitro DMSO 70 mg/mL (172.25 mM)
Water Insoluble
Ethanol 24 mg/mL (59.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.61 mL 123.04 mL 246.08 mL
0.5 mM 4.92 mL 24.61 mL 49.22 mL
1 mM 2.46 mL 12.3 mL 24.61 mL
5 mM 0.49 mL 2.46 mL 4.92 mL

*The above data is based on the productmolecular weight 406.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13551
Actions Inhibitor
CAS No. 449811-01-2
Formula C19H20F2N4O4
M. Wt 406.38
Solubility DMSO
Purity >98%
Synonyms R 1503, R1503, R-1503, Ro 4402257, Ro4402257, Ro-4402257
SMILES CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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