PC-PEG11-Azide is a PEG-based linker designed for use in PROTAC synthesis, facilitating targeted protein degradation. It features an Azide group that enables copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds. Additionally, PC-PEG11-Azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) derivatives. This versatility makes it a valuable tool for chemical biology and drug discovery applications.
PC-PEG11-Azide is a PEG-based linker designed for use in PROTAC synthesis, facilitating targeted protein degradation. It features an Azide group that enables copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds. Additionally, PC-PEG11-Azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) derivatives. This versatility makes it a valuable tool for chemical biology and drug discovery applications.
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