PCI-24781 (Abexinostat)

Catalog No.: A10700

HDAC Inhibitor

PCI-24781 (Abexinostat)

PCI-24781 (Abexinostat) Chemical Structure

CAS NO. 783355-60-2

PCI-24781 is a broad-spectrum phenyl hydroxamic acid HDAC inhibitor.

Availability: In stock Shipped in 7-10 Days

Package Price Qty
5 mg
$80.00
10 mg
$120.00
50 mg
$380.00
100 mg
$600.00
10mM * 1mL in DMSO
$100.00
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Biological Activity

PCI-24781 is a broad-spectrum phenyl hydroxamic acid HDAC inhibitor.
Targets
Target Value
HDAC1ki: 7nM
HDAC3/SMRTki: 8.2nM
HDAC6ki: 17nM
HDAC2ki: 19nM
HDAC10IC50: 24nM
HDAC8IC50: 280nM
In vitro DMSO 72 mg/mL (181.16 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.82 mL 251.64 mL
0.5 mM 5.03 mL 25.16 mL 50.33 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10700
Actions Inhibitor
CAS No. 783355-60-2
Formula C21H23N3O5
M. Wt 397.4
Purity >98%
Synonyms PCI24781, CRA-024781
SMILES CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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