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PD 123319 ditrifluoroacetate

Catalog No.: A13201
angiotensin AT2 receptor antagonist
Adooq's PD 123319 ditrifluoroacetate has been cited by 1 publications
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.
PD 123319 ditrifluoroacetate
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5mg
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$235.00
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$395.00
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100mg
$695.00
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200mg
$990.00
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10mM * 1mL in DMSO
$140.00
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Adooq Products cited in reputable paper
Adooq's PD 123319 ditrifluoroacetate has been cited by 1 publications
  • Dao-Lai Zhang, .et al. , eLife, 2018, 7: e33432 PMID: 29393851
    • Biological Activity
    Discription PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A13201
    Formula C31H32N4O3.2CF3CO2H
    Molecular Weight 736.67
    CAS Number 136676-91-0 (TFA), 130663-39-7
    SMILES CC1=C(C=CC(=C1)CN2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    Synonyms PD123319, PD-123319
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 87 mg/mL (171.05 mM)
    Water 87 mg/mL (171.05 mM)
    Ethanol 87 mg/mL (171.05 mM)
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 13.57 mL 67.87 mL 135.75 mL
    0.5 mM 2.71 mL 13.57 mL 27.15 mL
    1 mM 1.36 mL 6.79 mL 13.57 mL
    5 mM 0.27 mL 1.36 mL 2.71 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Endocrinology-Hormones > renin-angiotensin-aldosterone system (RAAS)
    GPCR/G Protein > Angiotensin Receptors
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