Peficitinib hydrobromide is a selective Janus kinase (JAK) inhibitor, exhibiting IC50 values of 3.9 nM for JAK1, 5.0 nM for JAK2, 0.7 nM for JAK3, and 4.8 nM for Tyk2. This compound is primarily utilized in research related to autoimmune diseases and inflammatory conditions, demonstrating potential therapeutic efficacy in modulating immune responses. Its oral bioavailability makes it a valuable tool for studying JAK signaling pathways in various biological models.
Peficitinib hydrobromide is a selective Janus kinase (JAK) inhibitor, exhibiting IC50 values of 3.9 nM for JAK1, 5.0 nM for JAK2, 0.7 nM for JAK3, and 4.8 nM for Tyk2. This compound is primarily utilized in research related to autoimmune diseases and inflammatory conditions, demonstrating potential therapeutic efficacy in modulating immune responses. Its oral bioavailability makes it a valuable tool for studying JAK signaling pathways in various biological models.
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