Pefloxacin mesylate dihydrate is a broad-spectrum antibiotic that primarily inhibits DNA gyrase, disrupting DNA replication. This compound demonstrates significant antibacterial activity against both Escherichia coli and Pseudomonas aeruginosa, with MIC90 values of 0.12 mg/L and 4 mg/L, respectively, and also targets Bacteroides fragilis with an MIC90 of 16 mg/L. Additionally, Pefloxacin mesylate dihydrate exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. Its diverse profile makes it a valuable tool for infection studies and related research applications.
Pefloxacin mesylate dihydrate is a broad-spectrum antibiotic that primarily inhibits DNA gyrase, disrupting DNA replication. This compound demonstrates significant antibacterial activity against both Escherichia coli and Pseudomonas aeruginosa, with MIC90 values of 0.12 mg/L and 4 mg/L, respectively, and also targets Bacteroides fragilis with an MIC90 of 16 mg/L. Additionally, Pefloxacin mesylate dihydrate exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. Its diverse profile makes it a valuable tool for infection studies and related research applications.
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