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Peplomycin sulfate

Catalog No.: A31894
Antitumor Antibiotic
Peplomycin sulfate is an antitumor antibiotic that acts by inducing DNA strand breaks, thereby promoting apoptosis in cancer cells. It exhibits significant antitumor activity while displaying relatively low pulmonary toxicity. Additionally, Peplomycin sulfate has been shown to induce various skin abnormalities and can lead to pulmonary fibrosis. This compound is valuable for research applications related to cancer, pulmonary fibrosis, and other associated diseases.
Peplomycin sulfate 70384-29-1 Antitumor Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPeplomycin sulfate is an antitumor antibiotic that acts by inducing DNA strand breaks, thereby promoting apoptosis in cancer cells. It exhibits significant antitumor activity while displaying relatively low pulmonary toxicity. Additionally, Peplomycin sulfate has been shown to induce various skin abnormalities and can lead to pulmonary fibrosis. This compound is valuable for research applications related to cancer, pulmonary fibrosis, and other associated diseases.
Product Information
Catalog NumA31894
FormulaC61H90N18O25S3
Molecular Weight1571.67
CAS Number70384-29-1
SMILESO=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@@](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCCN[C@H](C4=CC=CC=C4)C)=O)=CS3)=CS2)=O)=O)=O)([H])[C@H](C5=CNC=N5)O[C@H]6[C@H]([C@H]([C@H](O)[C@H](CO)O6)O)O[C@]7([H])[C@H]([C@H]([C@H](O)[C@@H](CO)O7)OC(N)=O)O.OS(O)(=O)=O
SynonymsBleomycin PEP sulfate; Pepleomycin sulfate
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Microbiology > Antifection > Antibiotic